Dietary Intervention in Infancy and Later Signs of Beta-Cell Autoimmunity
A journalist's write-up is here
Double-blind study on 230 infants with HLA-conferred susceptibility to type 1 diabetes and with at least one family member with type 1 diabetes, were split into test group fed casein hydrolizate based formula, and the control group fed conventional cow's milk based formula.
Autoantibodies to insulin, glutamic acid decarboxylase (GAD), the insulinoma-associated 2 molecule (IA-2), and zinc transporter 8 were analyzed, as well as monitored for the incidence of diabetes t1, until the age of 10.
The risk of developing diabetes t1 markers in the casein hydrolizate group was substantially reduced - by ~50%, compared with the control group reciving cow's milk formula!
Updated (14-Nov-2010) This is going to be a story of two food villains and one food hero.
There is more to milk that 1 paper. Much more: a study involving a billion people. The China study. I am going to dump some facts here for the reference.
My source of data is Mono Mortality document. A cursory look at all diseases with the focus on correlation with milk reveals that milk correlates positively with almost all diseases! The same cursory look reveals also that two other food items: wheat flour and eggs correlate very consistently too across most diseases,
one positively one negatively. Note: positive correlation means that an increase in consumption is associated with more disease and more harm, whereas negative correlation means an increase in consumption is associated with less risk of a disease. The main bullet points of this review are these:
* Wheat flour correlates positively with almost all diseases (except pulmonary TB in adults)
* Milk correlates positively with almost all diseases (except diabetes)
* Eggs correlate negatively with almost all diseases (except cancer, diabetes and IHD)
One should keep in mind that a correlation is no causuation, however the fact that milk and wheat and eggs correlate simultaneously and follow the same consistent pattern, albeit with different signs, may indicate that something real is going on in the human biochemistry in relation to those foods. This is a strong indication that more reseaarch should be made to investigate the effect. This is also a indictment against Cornell University that sat on such a rich set of data for a decade without doing anything usefull about it. (Other than letting one of their staff profesor hijack the study title to propagate his veganism!)
Here are some examples, I will list correlation factors from the above linked document, for disease mortalities against wheat, milk and eggs only. Correlation factors are given as two digit numbers in percentage, followed by the food item.
M015 Pullmonary TB (age 0-34):+34 Milk , -27 Eggs
M016 Pullmonary TB (age 35-69): -29 Wheat
M018 Other TB (age 35-69): +52 Wheat, -30 Eggs
M023 All cancer (age 35-69): +31 Eggs
M043 Endocrine (age 0-34): -36 Eggs
M044 Endocrine (age 35-69): -31 Milk
M045 Diabetes (age 35-69): -29 Milk, +26 Eggs
M050 Mental (age 0-34): +75% Milk
M059 All Vascular (age 35-69): +56 Wheat, +29 Milk, -26 Eggs
M060 Rheumatic (age 0-34): +37 Milk, -35 Eggs
M061 Rheumatic (age 35-69): +26 Wheat, -32 Eggs
M062 Hypertension (age 35-69): +43 Wheat, +75 Milk, -28 Eggs
M063 Ischaemic heart d.(age 35-69): +59 Wheat, +25 Eggs
M065 Stroke (age 35-69): +43 Wheat
M066 All vasc excl stroke (0-34): +33 Wheat, +42 Milk, -43 Eggs
M067 All vasc excl stroke (age 35-69):+65 Wheat, +50 Milk, -33 Eggs
M068 All respiratory (age 0-34): +50 Milk, -27 Eggs
M069 All respiratory (age 35-69): - (no correlation) -
M070 Pneumonia (age 0-34): +51 Milk, -27 Eggs
M071 Pneumonia (age 35-69): -32 Eggs
M087 Pregnancy and birth: +41 Wheat, +49 Milk, -48 Eggs
M104 Maternal mort.: +38 Wheat, +46 Milk, -42 Eggs