Artemisia Annua Sweet Wormwood - anti-cancer

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Ancient Chinese Salad Plant Transformed Into New Cancer-killing Compound

Quotes:

The artemisinin compound takes advantage of cancer cell's high iron levels. Artemisinin is highly toxic in the presence of iron, but harmless otherwise. Cancer cells need a lot of iron to maintain the rapid division necessary for tumor growth.

Since too much free-floating iron is toxic, when cells need iron they construct a special protein signal on their surfaces. The body's machinery then delivers iron, shielded with a protein package, to these signals proteins. The cell then swallows this bundle of iron and proteins.

Artemisinin alone is fairly effective at killing cancer cells. It kills approximately 100 cancer cells for every healthy cell, about ten times better than current chemotherapies. To improve those odds, the researchers added a small chemical tag to artemisinin that sticks to the "iron needed here" protein signal. The cancer cell, unaware of the toxic compound lurking on its surface, waits for the protein machinery to deliver iron molecules and engulfs everything -- iron, proteins and toxic compound.

Once inside the cell, the iron reacts with artemisinin to release poisonous molecules called free radicals. When enough of these free
radicals accumulate, the cell dies.

"The compound is like a little bomb-carrying monkey riding on the back of a Trojan horse," said Henry Lai, UW bioengineering professor and
co-author of the study.

The compound is so selective for cancer cells partly due to their rapid multiplication, which requires high amounts of iron, and partly because cancer cells are not as good as healthy cells at cleaning up free-floating iron.

"Cancer cells get sloppy at maintaining free iron, so they are more sensitive to artemisinin," Sasaki said.

References:


Synthesis and anti-cancer activity of covalent conjugates of artemisinin and a transferrin-receptor targeting peptide
Steve Oh, Byung Ju Kim, Narendra P. Singh, Henry Lai, Tomikazu Sasaki; February 8, 2009


Anticancer Effect of AntiMalarial Artemisinin Compounds,
AK Das; 2015 Mar-Apr


The Effects of Artemisinin on the Cytolytic Activity of Natural Killer (NK) Cells,
Youn Kyung Houh, Kyung Eun Kim, Sunyoung Park, Dae Young Hur, Seonghan Kim, Daejin Kim, Sa Ik Bang, Yoolhee Yang, Hyun Jeong Park, and Daeho Cho; 2017 Jul

Recovered raw data of old study undermines 40y of dietary dogma

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SciAm article: Records Found in Dusty Basement Undermine Decades of Dietary Advice
Raw data from a 40-year-old study raises new questions about fats
By Sharon Begley, STAT on April 19, 2017

Quote:

Ramsden, of the National Institutes of Health, unearthed raw data from a 40-year-old study, which challenges the dogma that eating vegetable fats instead of animal fats is good for the heart. The study, the largest gold-standard experiment testing that idea, found the opposite, Ramsden and his colleagues reported on Tuesday in BMJ (formerly the British Medical Journal).

Although the study is more than just another entry in the long-running nutrition wars—it is more rigorous than the vast majority of research on the topic—Ramsden makes no claims that it settles the question. Instead, he said, his discovery and analysis of long-lost data underline how the failure to publish the results of clinical trials can undermine truth.
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The coleader of the project was Dr. Ancel Keys, author of the Seven Countries Study, Time cover subject, and the most prominent advocate of replacing saturated fat with vegetable fat. “The idea that there might be something adverse about lowering cholesterol [via vegetable oils] was really antithetical to the dogma of the day,” Bob Frantz said.

His father, he said, “was always committed to discovering the truth. He would be pleased this is finally coming out.”

From The Telegraph "Modern dunce's cap"

I beg to differ. I doubt if Dr. Ivan Frantz would be proud of publishing the truth, because he could have but he didn't! I think he was afraid of the truth! Like many academics, intellectuals and most people I knew worked with.   Not only Dr. I. Frantz kept the study's most important data unpublished but also actively obfuscated it by publishing a misleading partial summaries and whitewashed watered-down inconclusive "conclusions".

Half-truth = full lie!

Because of Dr. Ivan Frantz' and other fake scientists' failure to publish the truth, What followed was 40-more years of suffering by millions of people from preventable diseases, due to bad dietary advise and corporate self-served food marketing that was based on the academically-supported half-truth, lies and distortions!

United Stated needs no external enemy - it is being destroyed by their own luminaries and the establishment through half-truth, lies and deception.

Bob Frantz, Dr. Franz's son, who rediscovered the hidden records and got them published, can't really feel proud of his father, but he definitely deserves to be proud of himself and be praised for bringing the truth! He is also lucky to have survived his father's bad diet at home, as a child.

Reference:
Appendix: Supplementary material [posted as supplied by author
Part 1: MCE supporting materials and historical context
Tribute to Dr. Ivan Frantz in leading the Minnesota Coronary Experiment team
Reared on Margarine and to the Tune of Spinning Ultracentrifuges:
A Son’s Recollections of Ivan D. Frantz, Jr. During the Early Days of Lipid Research
Robert P. Frantz, M.D.

Higher fish consumption less depression

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Original picture

Forbes: majority scientists consensus - not supporting Global Warming crisis!

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https://www.forbes.com/sites/jamestaylor/2013/02/13/peer-reviewed-survey-finds-majority-of-scientists-skeptical-of-global-warming-crisis

Quote:

It is becoming clear that not only do many scientists dispute the asserted global warming crisis, but these skeptical scientists may indeed form a scientific consensus.

Don’t look now, but maybe a scientific consensus exists concerning global warming after all. Only 36 percent of geoscientists and engineers believe that humans are creating a global warming crisis, according to a survey reported in the peer-reviewed Organization Studies. By contrast, a strong majority of the 1,077 respondents believe that nature is the primary cause of recent global warming and/or that future global warming will not be a very serious problem.

The survey results show geoscientists (also known as earth scientists) and engineers hold similar views as meteorologists. Two recent surveys of meteorologists (summarized here and here) revealed similar skepticism of alarmist global warming claims.

According to the newly published survey of geoscientists and engineers, merely 36 percent of respondents fit the “Comply with Kyoto” model. The scientists in this group “express the strong belief that climate change is happening, that it is not a normal cycle of nature, and humans are the main or central cause.”

An egg a day lowers cardiovascular death by 18%

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Associations of egg consumption with cardiovascular disease in a cohort study of 0.5 million Chinese adults

Quote:

Results
At baseline, 13.1% of participants reported daily consumption (usual amount 0.76 egg/day) and 9.1% reported never or very rare consumption (usual amount 0.29 egg/day). Compared with non-consumers, daily egg consumption was associated with lower risk of CVD (HR 0.89, 95% CI 0.87 to 0.92). Corresponding multivariate-adjusted HRs (95% CI) for IHD, MCE, haemorrhagic stroke and ischaemic stroke were 0.88 (0.84 to 0.93), 0.86 (0.76 to 0.97), 0.74 (0.67 to 0.82) and 0.90 (0.85 to 0.95), respectively. There were significant dose-response relationships of egg consumption with morbidity of all CVD endpoints (P for linear trend < 0.05). Daily consumers also had an 18% lower risk of CVD death and a 28% lower risk of haemorrhagic stroke death compared to non-consumers.

Wiki 

Biggest 2y global temperature drop in century

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Did You Know the Greatest Two-Year Global Cooling Event Just Took Place?

Fats don't kill - carbs kill!

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According to conclusions from the recent study published in The Lancet (thanks JC for the link).

Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study

A decade-long study on 135 thousand participants, examined mortality risk versus macronutrients correlations, based on reported food-questionaires. The findings:

1) Higher carbohydrate intake was associated with 28% increased risk of total mortality (highest quintile 5 vs lowest quintile 1 category).

2) Higher intake of total fat was associated with 23% lower risk of total mortality (quintile 5 vs quintile 1).

3) Total fat and saturated and unsaturated fats were not significantly associated with risk of myocardial infarction or cardiovascular disease mortality.

Quote:

"Global dietary guidelines should be reconsidered in light of these findings."

Source link , design by Trey Cox

The meatans

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Carnivore "vegans"

Wiki Steak

Quote:

They mock vegans and eat 4lb of steak a day: meet 'carnivore dieters'
An extreme, all animal-based diet is gaining followers in search of heightened productivity, mental clarity, and a boosted libido. But experts express doubts

Instagram: shawnbaker1967At 51 years of age I am well aware of the tremendous evidence that demonstrates maintaining as much lean muscle mass as possible is necessary to mitigate the risks of cardiovascular disease and promotes excellent metabolic health-I remain incredibly insulin sensitive with a fasting insulin of just 2.6 and maintain extremely low levels of inflammation with a hsCRPof on 0.6 and also have very low triglycerides levels of only 54- also my VO2max is also among the best in the world for my age based on my rowing capacity- it is the entire system and its overall function that best indicate health!

Everybody must watch The Magic Pill movie!

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Unsurprisingly, wheat and carbohydrate-pushing Australian Medical Association and fake pardon - mainstream media slammed it with unsubstantiated accusations:

'It's patently ridiculous, harmful and mean': Doctors slam celebrity chef Pete Evans' new paleo documentary that claims the 'caveman' diet can treat chronic diseases

Quote:

A new documentary by controversial celebrity chef Pete Evans which claims the paleo diet can treat chronic disease has been slammed by Australia's top doctors.
The film, The Magic Pill, claims people suffering from illnesses such as diabetes, cancer and autism can reduce their symptoms and reliance on prescription drugs by adopting the diet for just five weeks. Australian Medical Association president Michael Gannon has compared the documentary to controversial anti-vaccination film, Vaxxed, and said the two were competing 'in the awards for the films least likely to contribute to public health'. 'Elements of the discussion are just plain hurtful, harmful and mean,' Dr Gannon told The Daily Telegraph.

The AMA's outburst came after Evans stood by his outspoken views on the paleo diet during an interview on Channel Seven's Sunday Night program.
'This way of eating reverses Type 2 diabetes. And guess how quickly it takes? Six to eight weeks. Maybe three months,' he said.

Great Awakening has been going on for some time! I was regarded eccentric 19 years ago when I started eating this style - then I discovered that telling people to renounce the official "food pyramid" guidelines to cure their diseases was met with greater opposition than if I told them to renounce "Jesus". It is strange how people are addicted to carbs and to their diseases! You want to regain health - get rid of all that mainstream garbage!

Heretic

I am famous :)

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Stan Heretic Diet Scammer exposed. Okinawa Doesn't Mean 'Island of Pork'...

Vaccines

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Controversial subject, [to be expanded]


Dr. Jon Bergman says the flu vaccine is laced with cancer-causing ingredients

Little Ice Age revision 2.0

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See also this

Study: Solar Cycle To Cause A ‘Mini Ice Age’ As Early As 2020


Another theory bites the dust. CO2 level change is not the primary cause of temperatures variations, it is the result of it!

Interesting article on atmospheric CO2

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BBC ‘Scientists’ And The Greenhouse Gas Climate Fraud

Climate scam has become a real problem

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From the blog 

“Saving The Planet” Update : Wind Turbines Destroy Local Farming Village And Bees

CLIMATE alarmism’s primary objective is to scare you and policy makers into belief such that your taxes are effortlessly diverted, with little to no scrutiny, into research grants and green schemes and scams to supposedly stop bad weather by changing the temperature of the planet. Yet, no one can ever tell you by how much the temperature will change for each dollar spent. But alas, “Saving The Planet” is far more important than how your hard-earned money is spent, right?

CLIMATE research is paid for by you in the form of government grants. And, thanks to the system of pal peer-review, the most scary studies, prefaced by “anthropogenic” are given the green light, published in science journals with results interpreted by the compliant mainstream media and delivered back to you, to scare you even more such that you will happily donate more money to the scam research.

...

THE environmental movement bangs on about how important bees are to “existence as we know it”. So, maybe this microcosm of direct bee destruction might open the eyes of a few climate luvvies as to the clear and present danger that industrial wind turbines present to, not only peoples’ livelihoods and to their local economies, but to Gaia and her most precious workers ...

Scientist-made climate change magic

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Reposted from
@SteveSGoddard (on Twitter)

NASA 1999/2018 data tampering animation.
Global warming is indeed man-made - by government scientists tampering with the data.
US Temperature graph 1880-1999, from GISS analysis of surface temperature change
US Temperature graph 1880-2017

Fake climate marketing

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Der Spiegel 15/02/2018 article titled "Climate Change Disinformation. Catastrophe Business"

Desinformation zum Klimawandel; Das Geschäft mit der Katastrophe. Axel Bojanowski

English translations of the article quotes and comments are reposted after this blog:

Surprise! Spiegel Online Slams Profiteering From Climate Alarmism… Munich Re Admits: “No Climate Signal”

All have been playing it loose with the data on weather events and exaggerating (at times grossly) and with the aim of deriving profit, Spiegel reports.

German Railway: climate change as a cover for poor management

Bojanowski begins by describing how today the German Railway (Deutsche Bundesbahn) – once heralded for its outstanding punctuality and overall efficiency – has discovered how to use climate change to deflect blame away from its recent poor management, which over the years has often led to lousy service.

Over the years, the Bundesbahn has made the maintenance of its tracks a victim to cost cutting. Trees and vegetation along the tracks no longer get sufficiently cut back, and so it is common for routes to get blocked during stormy weather. What better excuse than climate change could the Deutsche Bahn have to explain all the disruptions?

Data in fact show no increasing trend in extreme weather

All the cancellations, service shutdowns and delays are of course due to ever increasing storm intensity and frequency, the Deutsche Bahn management likes to claim, and they get the full backing of the media, policymakers and alarmist climate scientists. Yet Bojanowski calls out these claims by the Bundesbahn for what they are: lame excuses based on hyped up science.

The Spiegel journalist writes that a number of scientists have shown that there has in fact been no increase in storm intensity and frequency in Europe, commenting:
That’s amazing, as many scientists anticipate fewer storms in Central Europe as a consequence of climate change.”


Munich Re bilking the public with climate hype?

Another industry caught hyping up extreme weather activity is the reinsurance industry, which insures regular insurance companies against major claims events. The reason for the added hype: justification for hefty premium increases, Bojanowski suggests.

Munich Re admits no real climate signal

One company Bojanowski cites is the world’s largest reinsurer, Munich Re, which annually publishes a report on “natural catastrophes”, in which the company likes to blame climate change, cite alarmist experts and claim there is today a “new normal”. When asked by Spiegel to comment concerning data showing that it isn’t really so, a climate expert from Munch Re was forced to admit:

The blanket statement that weather-dependent damages worldwide show a climate signal cannot be supported.”

...

Environmental companies spreading climate hype
Recently there was a panel of climate experts at the IFAT industrial trade fair for wastewater technology, which saw 3000 environmental companies participating. The panel held a “future dialog” dubbed: “Weather extremes – are we defenseless?” Bojanowski reports that the panel spoke of which weather extremes have been on the increase, but how they kept silent about this still being very much in dispute among climate scientists.
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Unmentioned by the panel, Bojanowski writes, was the fact that the UN “could not detect any relationship between floods and storms and global warming“.

and the last but not least comment from the blog itself:

Shameless exploitation/hypocrisy

Unfortunately Spiegel — in its otherwise praiseworthy article — failed to mention two other parties who have a major stake in climate hype: the media (like Spiegel itself), who have profited immensely from spectacular climate claims, and politicians, who unabashedly exploit climate catastrophism to try to gain more control over society.

Data graphs from the article.

ABC: Experts say flu shot potentially caused the flu epidemic

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ABC: Experts say flu shot potentially caused the flu epidemic (Shocker, in mainstream no less)
By Erin Elizabeth - February 8, 2018

New anti-viral melanoma therapy

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TV interview with medical doctor prof Andrzej Mackiewicz (in Polish)

Quote:

Oncologist prof. Andrzej Mackiewicz, creator of the melanoma vaccine, was a guest of "Dzien Dobry" ["Good Morning"] TVN program. It is a vaccine that heals, not just prevents melanoma! It could have helped several hundred sick people each year if it was officially registered and approved, however that is very expensive. Why is the melanoma vaccine not available to all patients? - We are scientists who have developed a medicine that works, and that seems to pose a huge problem for certain people or authorities - said prof. Mackiewicz on Good Morning TVN.

Non-interferon Hepatitis-C therapy

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Article (in Polish)

Quote (translated):

2. What is non-interferon therapy?

The non-interferon therapy involves the use of drugs that contain substances such as ombitasvir, paritaprevir, ritonavir (1 EAN code) and dasabuvu, which have maximum efficacy in the treatment of hepatitis C.

These modern drugs can be used in patients of all ages, regardless of the stage at which they have the disease. The patient requires constant medical supervision, however, hospitalization is not needed. This means that the patient is not exposed to stress and can undergo the therapy, which lasts from 12 to 24 weeks and costs about 60,000 zl (about 17600 US$). The therapy is completely safe and does not cause side effects, and most importantly - eliminates the virus in 90 to 100 percent of patients.

Older hepatitis C treatment therapies are much longer and more expensive - they last up to 72 weeks, and their cost often exceeds 160,000zl (47,200 US$).
In addition, they cause severe side effects - patients complain of very high fever, hair loss and skin problems. The success rate of healing hepatitis C with these older therapies is 70%.

New Ice Age?

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It is possible, the Sun is cooling!

Scientists warn of unusually cold Sun: Will we face another ice age?

Quote:

A study by the University of California San Diego has claimed that by 2050, the Sun is expected to become cool. You might think "what's the big deal," but remember that this means the solar activities that create the heat of the Sun to sustain life on Earth may diminish. And the last time it happened was in the 17th Century, when the Thames River froze. Scientists call this the "Maunder Minimum".

Physicist Dan Lubin at the university and his team studied the past event and concluded that were are in for a worse case. The Sun is expected to get much dimmer than last time and, in scientific terms, it is a "grand minimum" -- a time period in the 11-year solar cycle when the solar activities are at the lowest point.

Also read: Scientists warn of 'mini ice age' that could hit Earth and freeze major rivers by 2030

According to the study, titled Ultraviolet Flux Decrease Under a Grand Minimum from IUE Short-wavelength Observation of Solar Analogs and published in the journal Astrophysical Journal Letters, this grand minimum will be 7 percent cooler than such periods from the past.

I have to explain this. The effect if diminishing of the solar activity upon the atmophere is indirect. Even though the total energy flux is reduced by a small fraction of a percent, the total Sun light reaching the surface in some areas, especially the oceans may be reduced by a very large factor (tens percents) caused by increased cloud formation, the "cloud seeding" effect caused by increasing galactic cosmic rays flux striking the upper atmosphere. To summarize it, the causuality chain is as follows:

1) reduced Solar activity
2) reduced coronal flares
3) reduced intensity of the solar wind
4) reduced magnetic flux carried by the solar wind away from the sun out to the outer reaches of the solar system (beyond Kuiper Belt)
5) reduced solar magnetic flux means less shielding of the inner planets of the Solar System against high energy galactic particles ("Cosmic Rays")
6) less magnetic shielding means higher intensity of the Cosmic Rays seen at the Earth.
7) High energy cosmic ray particles cause microscopic condensation trails when striking the atmosphere.
8) The microscopic condensation trails cause water vapor condensation which leads to accelerated formation of clouds, accelerated - compared with the situation when there were no particle trails. Note that condensation by cosmic ray microtrails is the major factor in cloud seeding, another one are dust particles.
9) Increased rate of cloud formation causes higher average cloud coverage over the portions of the Earth surface, reflecting the Sunlight back out to space. Causing cooling of the climate.