Pfoizon's postmarketing experience

.The data is not fully verified.  I used the reference links and borrowed some words from this post Comment by Captain Sunset on Hyperlipid 

BNT162b2 / 5.3.6 Cumulative Analysis of Post-authorization Adverse Event Reports

Spike protein and cancer

"SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro" by Hui Jiang, Ya-Fang Mei, 2021 Oct 13

"53BP1: A key player of DNA damage response with critical functions in cancer", by Mohammad Mirza-Aghazadeh-Attariet al. Epub 2018 Nov 20

The Lancet paper on Ivermectin

 

The study found no difference between the treated group versus the control group in the viral load detected by PCR, but treated patients recovered twice as fast.  

Title:  "The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo-controlled, randomized clinical trial", by Carlos Chaccour et al., The Lancet, January 19, 2021

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30464-8/fulltext

The Lancet article on c19 spread by vac people

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The epidemiological relevance of the COVID-19-vaccinated population is increasing

An article published by Günter Kampf in The Lancet, Letters, 19-Nov-2021.

Quote:

High COVID-19 vaccination rates were expected to reduce transmission of SARS-CoV-2 in populations by reducing the number of possible sources for transmission and thereby to reduce the burden of COVID-19 disease. Recent data, however, indicate that the epidemiological relevance of COVID-19 vaccinated individuals is increasing. In the UK it was described that secondary attack rates among household contacts exposed to fully vaccinated index cases was similar to household contacts exposed to unvaccinated index cases (25% for vaccinated vs 23% for unvaccinated). 12 of 31 infections in fully vaccinated household contacts (39%) arose from fully vaccinated epidemiologically linked index cases. Peak viral load did not differ by vaccination status or variant type [[1]]. In Germany, the rate of symptomatic COVID-19 cases among the fully vaccinated (“breakthrough infections”) is reported weekly since 21. July 2021 and was 16.9% at that time among patients of 60 years and older [[2]]. This proportion is increasing week by week and was 58.9% on 27. October 2021 (Figure 1) providing clear evidence of the increasing relevance of the fully vaccinated as a possible source of transmission. A similar situation was described for the UK. Between week 39 and 42, a total of 100.160 COVID-19 cases were reported among citizens of 60 years or older. 89.821 occurred among the fully vaccinated (89.7%), 3.395 among the unvaccinated (3.4%) [[3]]. One week before, the COVID-19 case rate per 100.000 was higher among the subgroup of the vaccinated compared to the subgroup of the unvaccinated in all age groups of 30 years or more. In Israel a nosocomial outbreak was reported involving 16 healthcare workers, 23 exposed patients and two family members. The source was a fully vaccinated COVID-19 patient. The vaccination rate was 96.2% among all exposed individuals (151 healthcare workers and 97 patients). Fourteen fully vaccinated patients became severely ill or died, the two unvaccinated patients developed mild disease [[4]]. The US Centres for Disease Control and Prevention (CDC) identifies four of the top five counties with the highest percentage of fully vaccinated population (99.9–84.3%) as “high” transmission counties [[5]]. Many decisionmakers assume that the vaccinated can be excluded as a source of transmission. It appears to be grossly negligent to ignore the vaccinated population as a possible and relevant source of transmission when deciding about public health control measures.

AHA paper on cov. vac. - dramatic increase of cardiac risk markers

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Abstract 10712: Mrna COVID Vaccines Dramatically Increase Endothelial Inflammatory Markers and ACS Risk as Measured by the PULS Cardiac Test: a Warning

Steven R Gundry

Originally published8 Nov 2021Circulation. 2021;144:A10712

Quote: 

Abstract

Our group has been using the PLUS Cardiac Test (GD Biosciences, Inc, Irvine, CA) a clinically validated measurement of multiple protein biomarkers which generates a score predicting the 5 yr risk (percentage chance) of a new Acute Coronary Syndrome (ACS). The score is based on changes from the norm of multiple protein biomarkers including IL-16, a proinflammatory cytokine, soluble Fas, an inducer of apoptosis, and Hepatocyte Growth Factor (HGF)which serves as a marker for chemotaxis of T-cells into epithelium and cardiac tissue, among other markers. Elevation above the norm increases the PULS score, while decreases below the norm lowers the PULS score.The score has been measured every 3-6 months in our patient population for 8 years. Recently, with the advent of the mRNA COVID 19 vaccines (vac) by Moderna and Pfizer, dramatic changes in the PULS score became apparent in most patients.This report summarizes those results. A total of 566 pts, aged 28 to 97, M:F ratio 1:1 seen in a preventive cardiology practice had a new PULS test drawn from 2 to 10 weeks following the 2nd COVID shot and was compared to the previous PULS score drawn 3 to 5 months previously pre- shot. Baseline IL-16 increased from 35=/-20 above the norm to 82 =/- 75 above the norm post-vac; sFas increased from 22+/- 15 above the norm to 46=/-24 above the norm post-vac; HGF increased from 42+/-12 above the norm to 86+/-31 above the norm post-vac. These changes resulted in an increase of the PULS score from 11% 5 yr ACS risk to 25% 5 yr ACS risk. At the time of this report, these changes persist for at least 2.5 months post second dose of vac.We conclude that the mRNA vacs dramatically increase inflammation on the endothelium and T cell infiltration of cardiac muscle and may account for the observations of increased thrombosis, cardiomyopathy, and other vascular events following vaccination.

Scotland-UK gov report for Aug-Sep shows v. have very little effect on c. deaths

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It is interesting to note that "The Age Standardised Mortality Rate per 100,000" figures given in Table 18 (i.e. 8.38, 4.93, 1.93 for the unv., 1-va and 2-va, for the 11-17 of September) are inconsistent with the population va rates and the number of deaths in each category. These rates are probably adjusted and corrected for other factors. Unfortunately they did not explain (or I missed it) how exactly they were adjusted and corrected.

That's why I re-ran the numbers myself to verify them. I took the number of unv'ed people who died of c. (59) in the period, dividing them by the total number of people who died of c. (59+10+233=302, that is the total of unv'ed plus 1-v'ed plus 2-v'ed who died).  Divide 59 by 302 - you will get 20%. The actual percentage of those who died of c. and were double-v'ed is 77% (that is 233 by 302).

If you google the population stats for Scotland, for September, you will find that 22% are unv'ed, 78% are at least once v'ed (therefore 7% are exactly once-v.) and 71% are double v'ed.

To summarize it, 22% of the entire population are unv'ed and constitute 20% of those who died on c.

Double v'ed constitute 71% of the entire population and 77% of those who died on c.

Note that the percentage figures of 20% and 22% are statistically the same, within the statistical error (=+/- square root of N divided by N, for Gaussian distribution), so are the figures 70% and 77% - which indicates that the v. are not really effective in averting the c. deaths in Scotland.

Reference:

1/ SeeTable 18 in "Public Health Scotland C-XIX Statistical Report As at 27 September 2021"

Table 18 (from the above-report)

Age-Standardised Mortality Rate referenced in Table 18.

2/ C-XIX va. rates in Scotland, up to 10-Oct-2021, by Google search:

---- Update 24-Oct-2021 ----

Similar figures emerged from Israel.  Note: the following table provided by Dr. R. Malone has not been independently verified, as far as I know.

Update 3-Nov-2021, more references. 

3/ The UK data, similar to Scottish:

"COVID-19 vaccine surveillance report Week 42"

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1027511/Vaccine-surveillance-report-week-42.pdf

4/ https://www.thetimes.co.uk/article/mystery-rise-in-heart-attacks-from-blocked-arteries-m253drrnf

5/  https://chrismasterjohnphd.com/blog/2021/10/23/natural-immunity-vs-vaccination

6/ Updated 22/11/2021

Total deaths rates per 100k, for vaccinated and unvaccinated sub-populations. Allegedly based on the England's government sources, unverified!  [will add the source data reference later when I find them]

Vaccines and the innate and adaptive immune systems

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This is my first stab at learning about vaccines. How exactly they work, what do the "adjuvants" do?

Reference:

"Stabilising the Code" by Dr.Mike Williams, UKCOLUMN, 12th September 2021

"Impact of Polymer-TLR-7/8 Agonist (Adjuvant) Morphology on the Potency and Mechanism of CD8 T Cell Induction", Geoffrey M Lynn et al., Biomacromolecules. 2019 Feb 11;20(2):854-870.

In a nutshell - modification of the mRNA (nucleoside uridine code) in covid vaccine acts similar to  adjuvants (in other vaccines) weakening the innate immune system in order to give the chance for the adaptive immune system to activate, recognize and store the pathogen's signature.

That explains why vaccinating against a specific pathogen may make one vulnerable (for a time) to some secondary "opportunistic" infections. Or cancer...

Quotes:

In 2005, Drs. Weissman and Kariko discovered a way to protect foreign mRNA from the body’s immune system. That scientific milestone would be key to the advancement of the mRNA vaccines in 2020.

Recently, the University of Pennsylvania Tweeted a picture of the Drs. Weissman and Kariko receiving their Covid vaccination, and reminding us of that milestone. One tweet commenting that they should receive the Nobel prize for their discovery.

The fundamental change discovered by Weissman and Kariko was that nucleoside modification could protect mRNA from the body’s immune defences:

[picture]

Their key discovery, that by modifying the RNA code (modifying the nucleoside uridine), resulted in ablating the innate immune response, involved toll-like receptors (TLR).

This discovery was adopted in the mRNA technology used in Covid vaccines, in order that the foreign vaccine mRNA could enter cells without being destroyed.
...

By modifying the Uridine in the Pfizer vaccine mRNA code, the foreign mRNA is able to bypass part of the body’s first line of defence — the Innate Immune System.

The body possesses two broad parts to its immune system: innate and specific. The innate is the first to go into action against foreign invaders, including foreign mRNA from a vaccine.

How does that simple removal of one letter of code from mRNA achieve that? It does so by affecting Toll Like Receptors (TLR): the alarm signal of the Innate Immune System.

The key TLRs affected are TLR 3, TLR 7 and TLR 8. They act as sentries, whose job is to recognise foreign invaders by way of their form or patterns;
...

Dominguez-Andres et al addressed that question May 6th 2021. They state: ...

...
BNT162b2 vaccine also modulated the production of inflammatory cytokines by innate immune cells upon stimulation with both specific (SARS-CoV-2) and non-specific (viral, fungal and bacterial) stimuli. The response of innate immune cells to TLR4 and TLR7/8 ligands was lower after BNT162b2 vaccination.
...

We observed a significant reduction in the production if IFN-α secreted after stimulation with poly I:C and R848 after the administration of the second dose of the vaccine (Figure 1H, 1I). This may hamper the initial innate immune response against the virus, as defects in TLR7 have been shown to result in and increased susceptibility to COVID-19 in young males (Van Der Made et al., 2020). These results collectively demonstrate that the effects of the BNT162b2 vaccine go beyond the adaptive immune system and can also modulate innate immune responses.

Three concerns are raised by the above.

1. The ability of the immune system to fight viruses has been diminished; specifically, the ability to fight SARS-CoV-2 may be affected;
2. Vaccine-induced innate immune tolerance may affect other vaccines; and finally
3. What other parts of the immune system may be affected.

...
Dr Ryan Cole, a Pathologist, in a recent presentation, stated that he is observing a 20 x uptick in endometrial cancer, and increases in other cancers post SARS-CoV-2 vaccination.
...

The toll-like receptors 7 & 8 are described in the literature as important in eliciting the vital CD8 T cell response. With that in mind, let us remind ourselves what Drs. Weissman and Kariko wrote in 2005 in Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA:

We show that RNA signals through human TLR3, TLR7, and TLR8, but incorporation of modified nucleosides m5C, m6A, m5U, s2U, or pseudouridine ablates activity.

That very technology is being used in SARS-CoV-2 vaccines: It switches off TLR 7 & 8 signalling, that the immune system needs to fight infection and cancer.

Summary

Changes to key parts of the mRNA code in SARS-CoV-2 vaccines may be causal in changing the innate immune response via toll-like receptors. Toll-like receptors are important components in defence against infection and downstream effects may also include inhibition of CD8 T cell response. CD8 is a vital part of the immune system’s ability to eradicate infection and cancer. Those changes may be reflected in recent reactivated Varicella Zoster infections although specific mechanisms are unclear at the moment. Anecdotal reports of significant uptick in cancer presenting to medical consultants may be consistent with aberrant toll-like receptor and dendritic cell changes leading to an inhibition of the anti-cancer CD8 effector response. Further data are required but the prospect of an altered CD8 response to infection and cancer is very concerning and should prompt urgent investigation.
...

-------------------

Updated 2-Oct-2021

Another issue to investigate is cytokine storm and ADE (Anti-body Dependent Enhancement)

See the references in: "Mechanism behind rona virus damage"

smokers hospitalized less often for covid

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Smokers Hospitalized Less Often for COVID-19 By Carolyn Crist

The hypothesis comes from Konstantinos Farsalinos, a cardiologist in Greece who focuses on tobacco-use reduction. Farsalinos noticed that few COVID-19 patients who were hospitalized in China were smokers, though about half of men in the country smoke.
Farsalinos and colleagues wrote a new paper available as a preprint and scheduled to be published in Internal and Emergency Medicine. They found that among 13 studies in China with nearly 6,000 hospitalized COVID-19 patients, the rate of smokers ranged from 1.4% to 12.6%. No studies recorded e-cigarette use.
“The results were remarkably consistent across all studies and were recently verified in the first case series of COVID-19 cases in the U.S.,” the authors wrote, calling for an “urgent investigation.”
Of course, Farsalinos doesn't recommend that people should begin smoking simply to attempt to avoid a severe case of COVID-19.

Physical activity increases cardiovascular calcium score

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"Physical activity may increase heart attack risk, study suggests", The Irish Times, Sep 20, 2021, Paul Cullen

Note: "Calcium Score" they are refering to is also refered to as CAC Scan or Agatston Calcium Score. The reason Dr. Angie Brown quoted in the article was downplaying the "Calcium Score" method is, IMHO, because the results obtained by it are often contradictory to the prevailing medical paradigm. In spite of many cardiologists using it as very reliable diagnostics and risk assessment method. Quote:

The results suggested an overreliance on calcium scores and imaging alone may not be the best way to assess cardiovascular risk, said Dr Brown, a consultant cardiologist.

Unfortunately I was not yet able to locate the original (Korean) study, I will post the link when I find it.

Quote from the article:

To explore the issue further, the researchers studied healthy adults attending for check-ups in South Korea over a six-year period.
Those who were more physically active tended to be older and less likely to smoke than less physically active participants. They also had lower total cholesterol, more high blood pressure, and existing evidence of calcium deposits in their coronary arteries.
An association between physical activity level and the prevalence and progression of coronary artery calcification emerged over time. Higher physical activity was associated with faster progression of calcification scores.
Experts said the new study may mean that exercise increases the risk of a heart attack, or it may be that calcium build-up is not a good measure of heart attack risk.

Curious lack of discussion on natural immunity

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"Why ''Natural Immunity'' Is A Political Problem For The Regime", by CD Media StaffSeptember 24, 2021

Both the Mayo Clinic website and the Centers for Disease Control and Prevention website, for example, insist that “research has not yet shown” that people who have recovered from covid have any sort of reliable protection. Moreover, the CDC page points to a single study from Kentucky claiming that people with natural immunity are more than twice as likely to contract covid again, compared to people who have been vaccinated.

More than 15 studies have demonstrated the power of immunity acquired by previously having the virus. A 700,000-person study from Israel two weeks ago found that those who had experienced prior infections were 27 times less likely to get a second symptomatic covid infection than those who were vaccinated. This affirmed a June Cleveland Clinic study of health-care workers (who are often exposed to the virus), in which none who had previously tested positive for the coronavirus got reinfected. The study authors concluded that “individuals who have had SARS-CoV-2 infection are unlikely to benefit from covid-19 vaccination.” And in May, a Washington University study found that even a mild covid infection resulted in long-lasting immunity.

The policy bias in favor of vaccines ignores many other facts as well, such as the relative risks of vaccines, especially for the young:

The current Centers for Disease Control and Prevention position about vaccinating children also dismisses the benefits of natural immunity. The Los Angeles County School District recently mandated vaccines for students ages 12 and up who want to learn in person. But young people are less likely to suffer severe or long-lasting symptoms from covid-19 than adults, and have experienced rare heart complications from the vaccines. In Israel, heart inflammation has been observed in between 1 in 3,000 and 1 in 6,000 males age 16 to 24; the CDC has confirmed 854 reports nationally in people age 30 and younger who got the vaccine. ...

... For comparison, the CDC has long recommended that kids do not get the chickenpox vaccine if they had chickenpox infection in the past.

The nonscientific, ideology-induced blind spot for natural immunity also prompted The BMJ (the journal of the British Medical Association) to note that “[w]hen the vaccine rollout began in mid-December 2020, more than one quarter of Americans—91 million—had been infected with SARS-CoV-2…. As of this May, that proportion had risen to more than a third of the population, including 44% of adults aged 18–59.”

And yet, the authors note this fact doesn’t appear to be a part of any policy discussion at all:

The substantial number of infections, coupled with the increasing scientific evidence that natural immunity was durable, led some medical observers to ask why natural immunity didn’t seem to be factored into decisions about prioritising vaccination.

Dairy fat could PREVENT a heart attack

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Dairy fat from milk, butter, and cheese could actually PREVENT a heart attack SEPTEMBER 21,2021

“Many studies have relied on people being able to remember and record the amounts and types of dairy foods they have eaten, which is especially difficult given dairy is commonly used in a variety of foods,” says study co-author Dr. Matti Marklund from Uppsala University, in a statement.
“Instead, we measured blood levels of certain fatty acids, or fat ‘building blocks’ that are found in dairy foods, which gives a more objective measure of dairy fat intake that doesn’t rely on memory or the quality of food databases,” Dr. Marklund continues. “We found those with the highest levels actually had the lowest risk of CVD.”
... Researchers assessed dairy fat consumption in the group of Swedish 60-year-olds by measuring blood levels of a particular fatty acid. This substance generally appears in dairy foods and is therefore useful in reflecting intake of dairy fat. Study authors tracked the group for an average of 16 years to see how many had heart attacks, strokes, and other serious circulatory events. They also looked at how many died from any cause during this time.
The CVD risk was lowest for those with high levels of the fatty acid, coming from a high intake of dairy fats. The results remained the same after accounting for factors including age, income, lifestyle, dietary habits, and other illnesses. Moreover, those with the highest levels had no increased risk of death from all causes.

Reference
"Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis", Kathy Trieu , et al., PLOS MEDICINE, Published: September 21, 2021

Dr. Richard Urso on the smartest drug in history

"SMARTEST DRUG IN HISTORY", Dr. Richard Urso, first published at 16:02 UTC on May 27th, 2021.

David Diamond on Deception in Cholesterol Research: Separating Truth From Profitable Fiction

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The Song - Butter Makes Your Pants Fall Off

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Ivermectin and cancer

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Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations

Abstract Over the past decade, the global scientific community have begun to recognize the unmatched value of an extraordinary drug, ivermectin, that originates from a single microbe unearthed from soil in Japan. Work on ivermectin has seen its discoverer, Satoshi Ōmura, of Tokyo’s prestigious Kitasato Institute, receive the 2014 Gairdner Global Health Award and the 2015 Nobel Prize in Physiology or Medicine, which he shared with a collaborating partner in the discovery and development of the drug, William Campbell of Merck and Co. Incorporated. Today, ivermectin is continuing to surprise and excite scientists, offering more and more promise to help improve global public health by treating a diverse range of diseases, with its unexpected potential as an antibacterial, antiviral and anti-cancer agent being particularly extraordinary.

Ref added 3-Sep-2021: "Ivermectin, a potential anticancer drug derived from an antiparasitic drug", by Mingyang Tanga et al., Pharmacological Research, Volume 163, January 2021, 105207

Highlights

• Ivermectin effectively suppresses the proliferation and metastasis of cancer cells and promotes cancer cell death at doses that are nontoxic to normal cells.
• Ivermectin shows excellent efficacy against conventional chemotherapy drug-resistant cancer cells and reverses multidrug resistance.
• Ivermectin combined with other chemotherapy drugs or targeted drugs has powerful effects on cancer.
• The structure of crosstalk centered on PAK1 kinase reveals the mechanism by which ivermectin regulates multiple signaling pathways.
• Ivermectin has been used to treat parasitic diseases in humans for many years and can quickly enter clinical trials for the treatment of tumors.

Abstract Ivermectin is a macrolide antiparasitic drug with a 16-membered ring that is widely used for the treatment of many parasitic diseases such as river blindness, elephantiasis and scabies. Satoshi ōmura and William C. Campbell won the 2015 Nobel Prize in Physiology or Medicine for the discovery of the excellent efficacy of ivermectin against parasitic diseases. Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways. This suggests that ivermectin may be an anticancer drug with great potential. Here, we reviewed the related mechanisms by which ivermectin inhibited the development of different cancers and promoted programmed cell death and discussed the prospects for the clinical application of ivermectin as an anticancer drug for neoplasm therapy.

The mechanism behind rona virus damage

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The key factor is the Vitamin K-dependent protein S (PROS1). While the damage is caused by the viral spike S-protein.

References:

1. "Identification of the antithrombotic protein S as a potential target of the SARS-CoV-2 ...", Letter to Editor, Jan A. Ruzicka, Thrombosis Research 196 (2020) 257–259


2. Wiki Protein S


3. "Endothelial cell damage is the central part of C...-19 and a mouse model induced by injection of the S1 subunit of the spike protein", by Gerard J. Nuovo, et al., Ann Diagn Pathol. 2021 Apr; 51: 151682.


4. "SARS-COV-2 mRNA Vaccine (BNT162, PF-07302048) 2.6.4 Overview of Pharmacokinetic Test",


5. "The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier", by Tetyana P Buzhdygan, et al., Neurobiol Dis. 2020 Dec;146:105131. doi: 10.1016/j.nbd.2020.105131. Epub 2020 Oct 11.


6. "Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients", by Alana F Ogata, et al., Clinical Infectious Diseases, ciab465, Published: 20 May 2021


7. Talk by Dr. Byram Bridle on the "On-Point" program with Alex Pierson, 9:11, Posted on 27-May-2021


8. On-Point program with Alex Pierson, Globalnews Toronto

PROS1 has the following properties

TABLE.1: PROS1 PROPERTIES

PROS1
*	PROMOTES ANTI-THROMBOTIC STATE
*	AIDS IN SUPPRESSION OF COAGULATION
*	ACTIVATES TAM (RTK) DOWNREGULATING IMMUNE FUNCTION
*	SUPPRESSES INNATE IMMUNE FUNCTION
*	PREVENTS CYTOKINE STORM
*	IS SYNTHESIZED IN ENDOTHELIAL CELLS ALONGSIDE ACE2

TABLE.2: MECHANISM BEHIND SARS-CoV-2 (COVID-19) DAMAGE

SARS-CoV-2
1.	BINDS TO ACE2 PRODUCED IN ENDOTHELIUM, PENETRATES INTO ENDOTHELIAL CELLS
2.	DESTROYS ENDOTHELIUM REDUCING PRODUCTION OF PROS1 THERE
3.	REDUCTION OF PROS1 PROMOTES BOTH CLOTTING AND CYTOKINE STORM (RUNAWY IMMUNE RESPONSE)

Tables 1 and 2 are based on my understanding of paper [1].

The study [3] shows that the viral S-protein by itself (i.e. a "virion" - that is the spike S-protein without the viral RNA) may alone cause similar damage to the endothelial cells as described in the Table 2.

It seems this may have some big implications for the anti-viral measures that are based on the spike S-protein by itself. Regardless whether this involves injecting the S-protein alone, with a weak/disabled form of viral RNA or by making the body manufacture that protein by itself. It means that such measures may pose the similar threat for some patients, as the viral infection itself.

Quote from paper [3]:

... It is concluded that ACE2+ endothelial damage is a central part of SARS-CoV2 pathology and may be induced by the spike protein alone.

--- Updated 31-May-2021 ---

The Spike Protein - Dr. Byram Bridle Professor of Viral Immunology University of Guelph, 29-May-2021

Above video was censored by You Tube, below are some alternatives:

"I would probably prefer to have natural immunity" — Dr Byram Bridle (Viral Immunologist) February 24th, 2021

Alex talks with Dr. Byram Bridle, an Associate Professor on Viral Immunology at the University of Guelph about a new peer-reviewed study that suggests there may be terrifying reasons side effects such as heart inflammation, VITT, and other serious i…

Quote:

We have made a big mistake by incoculating people with the toxic spike-protein"

--- Updated 26-June-2021: "Bridging" or ADE (Anti-biody Dependent Enhancement) of infection ----

"Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures", by Nikolai Eroshenko et al., Nature Biotechnology volume 38, pages789–791 (2020)

Quote:

To the Editor - For certain diseases, patients who have been previously infected by one strain of a virus and who are later infected by another strain can suffer outcomes that are worse than those infected only once. One explanation for this phenomenon is that differences between two viral serotypes can compromise the ability of antibodies induced by the first infection to neutralize the second one; instead, the antibodies elicited by the first infection ‘bridge’ the second viral strain to immunoglobulin G (IgG) antibody constant region (Fc) receptors on immune cells, such as macrophages. Because this bridging is believed to enable viral entry into immune cells, shifting the tropism of the virus1, the outcome manifests as an antibody-dependent enhancement (ADE) of infection and a potentially more serious recurrence of disease. This phenomenon is often observed when antibody concentrations decrease as a result of waning immunity; an antibody may neutralize potently at high concentrations but cause enhancement of infection at sub-neutralizing concentrations.

More reference papers:

COVID-19 May Trigger Hyperglycemia and Worsen Disease by Harming Fat Cells OCTOBER 1, 2021

"Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2", by Moritz Reiterer et al., Cell Methabolism, September 15, 2021

Hydroxychloroquine and cancer

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I am posting it as a place-holder to prompt a further digging.

The original video presentation, quoting from memory because the original video depictued in the screenshot below, has been since deleted by youtube (and my account has been blocked by Twitter).

The presenter discussed an in-vitro study using human cultured tissues, with and without Нуdrохуснlоrоquin : (1) lung cancerous tissue (HeLa) and (2) kidney tissue (non-cancerous). The study found that c0rоna virus (normal cv non c19) would attack the lung and the kidney tissue without hcq, while the virus would only attack the cancerous lung tissue but not the non-cancerous kidney tissue when hcq is added.

Further and additional referenced, not the actual presentation:

Clinical Trials Using Hydroxychloroquine.

[TO BE FINISHED LATER]

Xenon narcolepsia in Kazakhstan

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Xenon induced narcolepsia cases in Kazakhstan a few years ago in a uranium mine village

I was watching a video blog report from a Kazakh village. It's in Russian and Polish describing a village and an abandon post-soviet town near an abandoned uranium mine. The vlogers interviewed an old uranium mining engineer, living besides the closed down uranium mine, saying (at 20m in the video) that "uranium is very healthy", he is 78y but was looking as if he were 60. He was saying all people, all his coworkers who retired and left the village are all dead!. Similarily, he said that of all people who were resettled from Chernobyl, many have died after just 4 years but those who remeined are alive!

https://www.youtube.com/watch?v=YlNXsMXct0M

Another woman said the same "Uranium is very healthy for the people liiving here". This old mining engineer said to the vloggers: "just stay here for 3 days and you will feel mych healthier and stronger!" He also said that all those who moved or were resettled to the cities are all dead! That was not the main subject, the purpose of the two young vloggers virsiting the old mining village was the mysterious sleeping epidemics that took place there. The epidemics only affected the village but not the nearby mining town.

Xenon dissolves hundred times more in fatty tissue than in water. That one person - a baker lady who was quite fat. I suspect (but have no evidence!) that those who suffered from sleeping episodes were obese people!

63 people out of the total village of ~700 fell ill. Each sleeping episode lasted a month. After about 1-2 years it went away.

The mining engineer thinks it was some gas from the mining ventillation shafts. The mine was disused at that time and flooded, he thinks that floodwater may have displaced and pushed gas. Strangely, it affected only the people not animals.

None reported any lasting problems. They talked to a baker woman who experienced it but looked healthy (overweight!) and didn't complain on anything.

One gas which can cause those symptoms (i.e. narcosis ) without any other side effects is Xenon and/or Krypton. They could be used as anastetics but are very expensive, better than Nitrous Oxide. Both are known daughterproducts of Uranium. Some people are probably accumulating those gases. They are not completely inert and can form clathrates.

Some alternative medical clinics/spa offer Xenon inhalations as therapy:

https://www.xenonclinic.com/en/effects-of-xenon-inhalation/

Xenon dissolves weakly in water but strongly in fats, which may explain its stronger effect on humans than animals (human brain contains mostly fat and is proportionally much bigger than in animals) and that it affects obese people more than thin.

This paper reports minimal effects on rabbits but more noticeable on humans!

https://science.sciencemag.org/content/113/2942/580

It is actually possible that the people in the village were soaked in Xenon (and/ perhaps also Krypton) emanated from the abandoned Uranium mine, and some people (perhaps those who carried more body fat) reacted more than the other. More sensitive. It is also interesting that the narcolepsia cases occured throughout the autumn and winter as the people started losing body fat releasing fat-dissolved Xenon back into their body tissues.

They didn't went completely comatose, just extreme lethargy. It could also explain a complete lack of toxicity, and lasting after effects, like for example happems with the CO and CO2 poissoning, or with hydrocarbons. Also hydrocarbons are smelly, while there nobody smelled anything! Noble gasses are odorless.

This paper is interesting: http://www.biomed.cas.cz/physiolres/pdf/56%20Suppl%201/56_S39.pdf

Quote:

The experiments show that besides anesthetic characteristics, xenon also has organ protective effect on heart and brain. The mechanism of this influence has not been sufficiently explained yet. According to a theory, brain damage after hypoxic/ischemic insult is caused by neuron apoptosis, which is influenced by the activation of N-methyl-D-aspartate receptor. It was demonstrated that xenon blocks this receptor. Therefore, xenon seems to be used for example in neonatal asphyxia (David 2003). After experimental occlusion of coronary artery performed in xenon anesthesia, quicker recovery of heart was demonstrated in comparison with total intravenous anesthesia (Hartlage 2004).

So xenon also -should- protect agains glutamate cascade caused by stress, which may explains its therapeuting effect by that Russian company using xenon inhalation therapy!

Xenon is expensive but not hugely expensive and it can be in practice, recirculated.

Xenon would work better, at least as admixture because of its neuro and cardio-protection!Heart surgery using Xenon as anesthetics produce no neurological deterioration, which is veru common follwing the standard cardiac surgeryThere was a paper I spotted.

Xenon is expensive but not prohibitively expensive and can be recirculated in a hospital setup using closed-system breathing apparatus. It could be a few % mixture only with the rest being He or N. I saw Xe pricing quoted of the order of 1eu/L.

It's interesting to notice how all the little snippets of this story fall together? The mechainsm could have been that of gradual absorption and then more rapid internal release. Those episode all begun late autumn early winter and ceased in the spring! Late fall is when temperature in Kazakhstan , in the open steppes fall rapidly down to -40C! So people begin suddenly lose their fat in the winter, suddenly releasing fat-dissolved Xenon gas.

[PROVISIONAL EDIT. - TODO: RE-EDIT AND FINISH]

Highly speculative musings on the cytokine storm, WWI typhus-lice plague, Spanish Flu and vacinasions

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Highly speculative musings on the cytokine storm, WWI thyfus-lice plague, Spanish Flu and vacinasions

During my morning meditations, I recall receiving 3 (at least) warnings from my High self during the last few years: the first one was a general warning against all vacxinations carried out in the last decade or so.

The second warning was a specific information that the anti-rona vaxine constitutes a 'binary" bioweapon that primes the immune system towards cytokine storm when triggered by another disease which could be c0rona virus or any other virus, or any other infection or allergy. People who get vakcines are exposed to a high risk of dying of a subsequent infection or an allergic shock.

The third information I got through meditations a few months ago was that a very similar natural (probably) a "double-whammy" mechanism was responsible for the Spanish flu deaths of 1918-1921. Except in that case the immune primer was the lice-carried typhus disease (rather than the vaksines) that became a common plague in the trenches and barracks of the WWI. So common that tyfus often overshadowed the flu on the Eastern front. Then the subsequent spread of normally less cold or flu would trigger a deadly cytokines storm causing a rapid death by asphyxation. A connection between insect bites and cytokine storm is worth a further investigationg, imho.

Low level radiation is cancer-protective

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Two papers:

1) https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1349-7006.1992.tb02342.x

Cancer Mortality Survey in a Spa Area (Misasa, Japan) with a High Radon Background Masaaki Mifune Tomotaka Sobue Hiroko Arimoto Yoshiaki Komoto Sohei Kondo Hiroshi Tanooka First published: January 1992

2) https://www.birpublications.org/doi/full/10.1259/bjr.75.895.750637

BJR > Previous Issues > Volume 75, Issue 895 > Radiation increased the longevity of British radiologists Correspondence Radiation increased the longevity of British radiologists J R Cameron 2678 SW 14th Drive, Gainesville, FL 32608, USA