sugar addiction - drug-like effects

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Sugar addiction: is it real? A narrative review

Abstract
In animal studies, sugar has been found to produce more symptoms than is required to be considered an addictive substance. Animal data has shown significant overlap between the consumption of added sugars and drug-like effects, including bingeing, craving, tolerance, withdrawal, cross-sensitisation, cross-tolerance, cross-dependence, reward and opioid effects. Sugar addiction seems to be dependence to the natural endogenous opioids that get released upon sugar intake. In both animals and humans, the evidence in the literature shows substantial parallels and overlap between drugs of abuse and sugar, from the standpoint of brain neurochemistry as well as behaviour.

Vegan psychopath

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Pennsylvania Vegan Loses Food Truck Business After Celebrating Murder of ‘Meat Eaters’ in Las Vegas

Collectivism - protective anti-identity intellectual camouflage

Very interesting discussion, Camille Paglia & Jordan B Peterson

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Very interesting general idea, on the origin of human collectivism. See this discussion in the video, around minute 25 to 26, refering to dr. Robert Sapolsky's work on herd animals.

There are two forms of camouflage: one is to camouflage against the surrounding environment such as grass (i.e. the lions) another is to camouflage against the surrounding herd to become indistinguishable (i.e. zebras).  The authors discuss the emergence of modern academic collectivism and conformity as a form of intellectual  camouflage for the purpose of protecting positions and tenures, making oneself so undistinguishable from each other such as to thwart a potential intellectual attack against any one, making it as difficult as attacking the entire academic herd.     

Lectins are the reason wheat is harmful!

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It is not the new news but it will probably come up as a surprize to many people reading this blog. Repetition is the essence of learning.

Antinutritive effects of wheat-germ agglutinin and other N-acetylglucosamine-specific lectins.

Abstract

Incorporation of N-acetylglucosamine-specific agglutinins from wheat germ (Triticum aestivum; WGA), thorn apple (Datura stramonium) or nettle (Urtica dioica) rhizomes in the diet at the level of 7 g/kg reduced the apparent digestibility and utilization of dietary proteins and the growth of rats, with WGA being the most damaging. As a result of their binding and endocytosis by the epithelial cells of the small intestine, all three lectins were growth factors for the gut and interfered with its metabolism and function to varying degrees. WGA was particularly effective; it induced extensive polyamine-dependent hyperplastic and hypertrophic growth of the small bowel by increasing its content of proteins, RNA and DNA. Furthermore, an appreciable portion of the endocytosed WGA was transported across the gut wall into the systemic circulation, where it was deposited in the walls of the blood and lymphatic vessels. WGA also induced the hypertrophic growth of the pancreas and caused thymus atrophy. Although the transfer of the gene of WGA into crop plants has been advocated to increase their insect resistance, as the presence of this lectin in the diet may harm higher animals at the concentrations required to be effective against most pests, its use in plants as natural insecticide is not without health risks for man.

Full text PDF



More on the subject:

1) This blog

2) Dr. Mercola and Dr. Gundry on Plant Lectins (Full Interview)

3) Peter the Hyperlipid blog (for more refs to serious research papers, begin with this link!)

Low fat diet rises risk of early death by a quarter

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New study reported here:

•  Laura Donnelly, health editor, in barcelona 

29 AUGUST 2017 • 11:39AM

Low-fat diets could raise the risk of early death by almost one quarter, a major study has found.

The Lancet study of 135,000 adults found those who cut back on fats had far shorter lives than those enjoying plenty of butter, cheese and meats.

Researchers said the study was at odds with repeated health advice to cut down on fats.

Reference:

Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study

Quote:

Findings
During follow-up, we documented 5796 deaths and 4784 major cardiovascular disease events. Higher carbohydrate intake was associated with an increased risk of total mortality (highest [quintile 5] vs lowest quintile [quintile 1] category, HR 1.28 [95% CI 1.12–1.46], ptrend=0.0001) but not with the risk of cardiovascular disease or cardiovascular disease mortality. Intake of total fat and each type of fat was associated with lower risk of total mortality (quintile 5 vs quintile 1, total fat: HR 0.77 [95% CI 0.67–0.87], ptrend<0.0001; saturated fat, HR 0.86 [0.76–0.99], ptrend=0.0088; monounsaturated fat: HR 0.81 [0.71–0.92], ptrend<0.0001; and polyunsaturated fat: HR 0.80 [0.71–0.89], ptrend<0.0001). Higher saturated fat intake was associated with lower risk of stroke (quintile 5 vs quintile 1, HR 0.79 [95% CI 0.64–0.98], ptrend=0.0498). Total fat and saturated and unsaturated fats were not significantly associated with risk of myocardial infarction or cardiovascular disease mortality.

----- Update 8/09/2017 -----
Another article, from the NYT, commenting on that study:

New Study Favors Fat Over Carbs

Quote:

Compared with people who ate the lowest 20 percent of carbohydrates, those who ate the highest 20 percent had a 28 percent increased risk of death. But high carbohydrate intake was not associated with cardiovascular death.
People with the highest 20 percent in total fat intake - an average of 35.3 percent of calories from fat - had about a 23 percent reduced risk of death compared with the lowest 20 percent (an average of 10.6 percent of calories from fat). Consuming higher saturated fat, polyunsaturated fat and monounsaturated fat were all associated with lower mortality. Higher fat diets were also associated with a lower risk of stroke.

Study finds vegetarians have twice the rate of depression

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A new study by Bristol University of almost 10,000 men in the south west of England:

Vegetarian diets and depressive symptoms among men

The study full text is paywalled but a Daily Mail article describing the study says this:

Quote:

A study by Bristol University of almost 10,000 men in the south west of England found that those who gave up meat were almost twice as likely to suffer depression as those on a conventional balanced diet. It found the 350 committed vegetarians had a higher average depression score compared to others.

The paper, in the Journal of Affective Disorders, said a veggie diet led to lower intake of vitamin B12 and greater consumption of nuts rich in omega-6 fatty acids, which may be linked with greater risk of mental health problems. The report added: ‘Other potential factors include high blood levels of phytoestrogens – consequent mainly on diets rich in vegetables and soya. Another potential contributing factor is that lower intakes of seafood are thought to be associated with greater risk of depressive symptoms.’ Around one in 20 Britons are committed vegetarians and the majority are women.

New report casts doubts on validity of NOAA, NASA global temperature data

Indicating a possibility that the publications and data used to justify the recent Climate Change initiatives such as Paris Accord may have been falsified!

"On the Validity of NOAA, NASA and Hadley CRU Global Average Surface Temperature Data & The Validity of EPA’s CO2 Endangerment Finding"
Abridged Research Report,
Dr. James P. Wallace III, Dr. Joseph S. D’Aleo, Dr. Craig D. Idso, June 2017

ABSTRACT
The objective of this research was to test the hypothesis that Global Average Surface Temperature (GAST) data, produced by NOAA, NASA, and HADLEY, are sufficiently credible estimates of global average temperatures such that they can be relied upon for climate modeling and policy analysis purposes.
...
The conclusive findings of this research are that the three GAST data sets are not a valid representation of reality. In fact, the magnitude of
their historical data adjustments, that removed their cyclical temperature patterns, are totally inconsistent with published and credible U.S. and other temperature data. Thus, it is impossible to conclude from the three published GAST data sets that recent years have been the warmest ever –despite current claims of record setting warming. Finally, since GAST data set validity is a necessary condition for EPA’s GHG/CO2 Endangerment Finding, it too is invalidated by these research findings.

An article published yesterday in zerohedge.com summarizes the results as follows, quote:

As world leaders, namely in the European Union, attack President Trump for pulling out of the Paris Climate Agreement which would have saddled Americans with billions upon billions of dollars in debt and economic losses, a new bombshell report that analyzed Global Average Surface Temperature (GAST) data produced by NASA, the NOAA and HADLEY proves the President was right on target with his refusal to be a part of the new initiative.

According to the report, which has been peer reviewed by administrators, scientists and researchers from the U.S. Environmental Protection Agency (EPA), The Massachusetts Institute of Technology (M.I.T.), and several of America’s leading universities, the data is completely bunk: ...

__________________________

Update 6-Aug-2017

TEMPERATURE READINGS PLUNGE AFTER AUSTRALIA’S BUREAU OF METEOROLOGY ORDERS END TO ‘TAMPERING’

Quote:

Graham Lloyd, The Australian
Recorded temperatures at the Bureau­ of Meteorology’s Thredbo Top automatic weather station have dropped below -10C in the past week, after action was taken to make the facility “fit for ­purpose”.
A record of the Thredbo Top station for 3am on Wednesday shows a temperature reading of -10.6C. This compares with the BoM’s monthly highlights for June and July, both showing a low of -9.6C.
The BoM said it had taken immed­iate action to replace the Thredbo station after concerns were raised that very low temperatures were not making it onto the official record. Controversy has dogged the bureau’s automatic weather station network since Goulburn man Lance Pigeon saw a -10.4C reading on the BoM’s website on July 2 automatically adjust to -10C, then disappear.
Later independent monitoring of the Thredbo Top station by scientist Jennifer Marohasy showed a recording of -10.6C ­vanish from the record.
...

Study: chemotherapy may spread cancer and trigger more aggressive tumours

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http://www.telegraph.co.uk/science/2017/07/05/chemotherapy-may-spread-cancer-trigger-aggressive-tumours-warn/

Researchers in the US studied the impact of drugs on patients with breast cancer and found medication increases the chance of cancer cells migrating to other parts of the body, where they are almost always lethal.

Many are given chemotherapy before surgery, but the new research suggests that, although it shrinks tumours in the short term, it could trigger the spread of cancer cells around the body.

It is thought the toxic medication switches on a repair mechanism in the body which ultimately allows tumours to grow back stronger. It also increases the number of ‘doorways’ on blood vessels which allow cancer to spread throughout the body.

Dr George Karagiannis, of the Albert Einstein College of Medicine of Yeshiva University, New York, found the number of doorways was increased in 20 patients receiving two common chemotherapy drugs.

Study: highest glycemic diet - lung cancer twice as likely

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Article:

Warning: Some High Carb Foods Can Give You Lung Cancer

Quote:

The investigators looked specifically at the intake of foods with a high glycemic index, such as the white bread and potatoes cited by Jain.

Overall, people who registered in the top fifth in terms of a high-glycemic diet had a 49 percent greater risk of developing lung cancer versus those in the bottom fifth, Wu’s team reported.

And when the researchers focused solely on people who never smoked, the link was even more compelling. Those who had the highest glycemic diet were more than twice as likely to get lung cancer as those who had the lowest glycemic index scores.

The study:

"Glycemic Index, Glycemic Load, and Lung Cancer Risk in Non-Hispanic Whites",
Stephanie C. Melkonian, Carrie R. Daniel, Yuanqing Ye, Jeanne A. Pierzynski, Jack A. Roth and Xifeng Wu

Silicon Valley's elite are flocking to an extreme high-fat diet in hopes of living longer

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They flipped! Finally it happened!!! Since its on television then it has to be true (hey Mr. Citizen now you can believe it!)

Silicon Valley's elite are flocking to an extreme high-fat diet in hopes of living longer


Me first, then my wife and our four girls begun following the high animal fat, moderate protein low carb diet, based on dr. Jan Kwasniewski's "Optimal Diet", in July 1999, and stayed on it ever since. Initially I started it a fact finding mission after one of our friends enthusiastically recommended it, saying that it cured his liver cirrhosis in 6 months!

Actually it did!

I couldn't believe it since it violated every common medical "wisdom" raining down on us from every media outlet, as well as all doctors we spoke to. I like that aspect... After two weeks I felt better, stronger, more energy, clearer thinking, no tiredness - better than I ever did since my 20-ties! In addition a number of ailments went away, for example dry eye condition, afternoon tiredness, persistent (but not acute) intestinal inflammation etc.

Then my wife and our children begun eating this style, then my mother who lived with us. She begun a month after me, begrudgingly after we ran out of bread since my wife stopped buying it. How my mom recovered her chronic health problems on the high fat diet and what exactly happened - that's another story! We continuet that eating style ever since. It works for us. Back in 1999 everybody thought I was crazy, they were seriously expecting me to drop dead withing months (which, to their surprise, did not happen!)  When I begun my day job in 2009 half of my work colleagues were on some kind of "healthy" low fat salads and fruit for lunch or skim milk cereal diet, many were vegetarians (although there are fewer now) who wouldn't talk to me when I revealed my "orientation". Some still don't !    😊

Heretic

Saturated fat does not clog the arteries

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Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions FREE
Aseem Malhotra1⇑, Rita F Redberg2,3, Pascal Meier4,5

Quote:

Coronary artery disease pathogenesis and treatment urgently requires a paradigm shift. Despite popular belief among doctors and the public, the conceptual model of dietary saturated fat clogging a pipe is just plain wrong. A landmark systematic review and meta-analysis of observational studies showed no association between saturated fat consumption and (1) all-cause mortality, (2) coronary heart disease (CHD), (3) CHD mortality, (4) ischaemic stroke or (5) type 2 diabetes in healthy adults.1 Similarly in the secondary prevention of CHD there is no benefit from reduced fat, including saturated fat, on myocardial infarction, cardiovascular or all-cause mortality.2 It is instructive to note that in an angiographic study of postmenopausal women with CHD, greater intake of saturated fat was associated with less progression of atherosclerosis whereas carbohydrate and polyunsaturated fat intake were associated with greater progression.3

Study contradicts official guidelines promoting low salt intake

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Another mainstream medical theory bites the dust! Just like with the cholesterol-and-fat bull..t in the past - it will be interesting to find out what has gone wrong and who did it!   :)

Higher sodium intake associated with lower blood pressure.

PUBLIC RELEASE: 25-APR-2017
Low-sodium diet might not lower blood pressure
Findings from large, 16-year study contradict sodium limits in Dietary Guidelines for Americans

Quotes:

Chicago (April 25, 2017) - A new study that followed more than 2,600 men and women for 16 years found that consuming less sodium wasn't associated with lower blood pressure. The new findings call into question the sodium limits recommended by the current Dietary Guidelines for Americans.

Lynn L. Moore, DSc, associate professor of medicine at Boston University School of Medicine, will present the new research at the American Society for Nutrition Scientific Sessions and annual meeting during the Experimental Biology 2017 meeting, to be held April 22-26 in Chicago.

"We saw no evidence that a diet lower in sodium had any long-term beneficial effects on blood pressure," said Moore. "Our findings add to growing evidence that current recommendations for sodium intake may be misguided."

Is vegetarianism an eating disorder?

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From Wiki 

After reading this article, especially the reference papers, my conclusion is 'yes'!

ttp://www.brendadavisrd.com/eating-disorders-in-vegans-and-other-vegetarians-setting-the-record-straight/

Quote:

Many experts believe that vegan diets (and other types of vegetarian diets) can increase the risk of eating disorders. Some treatment centers consider the reintroduction of meat a necessary part of recovery. These beliefs are based on data released between 1997 and 2009 that reported significantly higher rates of disturbed-eating attitudes and behaviors, restrained eating, and disordered eating among vegetarians compared to nonvegetarians.1-5
Currently, approximately 50 percent of adolescents and young women with anorexia nervosa eat some form of vegetarian diet; whereas only 6 to 34 percent of their nonanorexic peers in the general population eat a vegetarian diet.6

References

1. Lindeman M et al. Vegetarianism and eating-disordered thinking. Eating Disorders. 2000; 8(2):157–165. 85.

2. Bas M et al. Vegetarianism and eating disorders: Association between eating attitudes and other psychological factors among Turkish adolescents. Appetite. 2005; 44(3):309–315.

As a conclusion, the present study indicated abnormal eating attitudes, low self-esteem, high social physique anxiety, and high trait anxiety in Turkish vegetarian adolescents. The vegetarian adolescents may be more likely to display disordered eating attitudes and behaviors than nonvegetarians.

3. Klopp SA et al. Self-reported vegetarianism may be a marker for college women at risk for disordered eating. Journal of the American Dietetic Association. 2003; 103(6):745–747.

A significantly higher (P less than 0.0001) proportion of the vegetarians (37%) compared with nonvegetarians (8%) had EAT scores greater than 30 (indicating eating disorder risk). There was no difference in supplement use or meal skipping between the two groups. In conclusion, self-reported vegetarian college women may be more likely to display disordered eating attitudes and behaviors than nonvegetarians.

  4. Neumark-Sztainer D et al. Adolescent vegetarians. A behavioral profile of a schoolbased population in Minnesota.  Archives of Pediatrics and Adolescent Medicine. 1997 Aug;151(8):833-8.

Vegetarians were almost twice as likely to report frequent dieting (P less than  .001), 4 times as likely to report intentional vomiting (P less than .001), and 8 times as likely to report laxative use (P less than .001) than nonvegetarians. Overall, associations with other health-compromising and health-promoting behaviors were not apparent. 

5.  Robinson-O’Brien R et al. Adolescent and young adult vegetarianism: better dietary intake and weight outcomes but increased risk of disordered eating behaviors. J Am Diet Assoc. 2009;109(4):648–55.

This study shows that in a group of 17 year old, binge eating with loss of control occurs among 21.2% (current vegetarians), 16.0%(former vegetarians) and 4.4%(never-vegetarians).

6. Bardone-Cone AM et al. The inter-relationships between vegetarianism and eating disorders among females. J Acad Nutr Diet. 201;112(8):1247–52.

Compared to controls, individuals with an eating disorder history were significantly more likely to ever have been vegetarian (52% vs. 12%), to be currently vegetarian (24% vs. 6%), and to be primarily motivated by weight-related reasons (42% vs. 0%). The three recovery status groups (fully recovered, partially recovered, active eating disorder) did not differ significantly in percentiles endorsing a history of vegetarianism or weight-related reasons as primary, but they differed significantly in current vegetarianism (33% of active cases, 13% of partially recovered, 5% of fully recovered). Most perceived that their vegetarianism was related to their eating disorder (68%) and emerged after its onset.

High fat diet appears to regenerate diabetic pancreas

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Is this possibly a cure for diabetes type 1 ?    According to this BBC article and the quoted study, it may be so!

Interestingly, dr. Jan Kwasniewski , creator of the "Optimal Diet" has always claimed that such diet can virtually cure about 9 out of 10 of diabetes type 1, based on his personal patient's records from his own medical practice during 1970-ties and 1980-ties. The reason, according to him, is that in most cases, there are at least residual 10% of the pancreatic beta cells still intact allowing the patient to survive on the high fat diet, on about 6 insulin units per day, which is about 10% of the normal (on a high carb diet) insulin production. Such low insulin requirements is only attainable on a diet that is very low in carbohydrates, low in protein and therefore - high in fat. Dr. Kwasniewski always recommended to eat mostly animal fat and saturated fats, with a minimal to none contents of polyunsaturated vegetable oils. This is interesting because that was back in the days when the  negative impact of polyunsaturated oils upon health was not as widely known as it is now. I always admired his medical insights ever since I learned about and adopted his diet in 1999. Since I don't normally trust opinions and always try to "touch the wound", so to speak, I always made efforts to verify and test all his claims. Every time when I thought he may have been wrong about some details such as vegetable fats issue or his preference on saturated fats, or insistence that cholesterol is a good thing and egg yolks are the best food (back in the 1970-ties!) - sooner or later he turned out to have been correct!

Heretic

Quantum processing in brain via phosphorus nucleons' spin

There is a revolution in physics going on, regarding research on the nature of consciousness, neural transmission and signal processing in the brain.  This seems like a very  important paper:

IS QUANTUM PROCESSING OPERATIVE IN THE BRAIN?
by Matthew Fisher

https://www.perimeterinstitute.ca/quantum-processing-operative-brain


Quote:

THE HYPOTHESIS

Fisher's theory of quantum entanglement in the brain starts with the chemical compound pyrophosphate.

Known to be essential for cellular function, pyrophosphate is made of two bonded phosphates, each made up of phosphorus (which has a nuclear spin of ½) and oxygen (which has a spin of zero).

When pyrophosphate is broken down by enzymes, the bonded pair of phosphate ions separates.

Pairs of spin-½ particles can combine in one of four ways. Three combinations lead to a total spin of one, and these are called triplet states. The fourth leads to a spin of zero, or a "singlet state," which is a special state of entanglement often referred to as the currency of quantum computing.

The enzyme catalysis of pyrophosphate occurs more often, and possibly only, if the bonded phosphate ions are in a singlet state. These entangled ions could then be "taken up" by nanometre-diameter-sized Posner molecules. Made up of six phosphate ions bound to nine calcium ions, Posner molecules have been identified in simulated body fluid and are thought to be present in the body.

The other ingredients in Posner molecules – calcium and oxygen – do not have a nuclear spin, and the small molecules are very spherical, thus are expected to tumble rapidly in water. This means the quantum entanglement of the phosphate ions is expected to be highly protected from its environment, and could remain coherent for a day or much longer.

With Posner molecules serving as a "qubit memory," the end result could lead to non-local quantum correlations – what Einstein called "spooky action at a distance" – in neurotransmitter release and postsynaptic firing across multiple neurons. This is what Fisher calls quantum cognition.

See also


Neural qubits: Quantum cognition based on synaptic nuclear spins
August 27, 2015 by John Hewitt report

https://phys.org/news/2015-08-neural-qubits-quantum-cognition-based.html


______________________________________________________

Can Quantum Physics Explain Consciousness?
A new approach to a once far fetched theory is making it plausible that the brain functions like a quantum computer.

by JENNIFER OUELLETTE NOV 7, 2016

https://www.theatlantic.com/science/archive/2016/11/quantum-brain/506768/

From Atlantic, Nov-2016

_____________________________________________________


Quantum Cognition: The possibility of processing with nuclear spins in the brain

Matthew P. A. Fisher
(Submitted on 19 Aug 2015 (v1), last revised 29 Aug 2015 (this version, v2))

https://arxiv.org/abs/1508.05929

Abstract:

The possibility that quantum processing with nuclear spins might be operative in the brain is proposed and then explored. Phosphorus is identified as the unique biological element with a nuclear spin that can serve as a qubit for such putative quantum processing - a neural qubit - while the phosphate ion is the only possible qubit-transporter. We identify the "Posner molecule", Ca9(PO4)6, as the unique molecule that can protect the neural qubits on very long times and thereby serve as a (working) quantum-memory. A central requirement for quantum-processing is quantum entanglement. It is argued that the enzyme catalyzed chemical reaction which breaks a pyrophosphate ion into two phosphate ions can quantum entangle pairs of qubits. Posner molecules, formed by binding such phosphate pairs with extracellular calcium ions, will inherit the nuclear spin entanglement. A mechanism for transporting Posner molecules into presynaptic neurons during a "kiss and run" exocytosis, which releases neurotransmitters into the synaptic cleft, is proposed. Quantum measurements can occur when a pair of Posner molecules chemically bind and subsequently melt, releasing a shower of intra-cellular calcium ions that can trigger further neurotransmitter release and enhance the probability of post-synaptic neuron firing. Multiple entangled Posner molecules, triggering non-local quantum correlations of neuron firing rates, would provide the key mechanism for neural quantum processing. Implications, both in vitro and in vivo, are briefly mentioned.

___________________

Was the Climate Action Plan a population reduction in disguise?

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The new US president is said to have removed all references to global warming/curbing carbon emission initiative, from the government website!

Had the world governments succeeded depleting carbon dioxide, it would speed up the coming of the new ice age. It may still happen. Ice age is the greatest threat to humanity and the biosphere, since a cold climate means not only more ice but it means also a dry climate!

Double whammy - first the Earth would loose most of the agricultural viable land in the Northern temperate climates, then it would cause desertification of the tropical areas causing a further damage to agriculture. Result: dramatic reduction of the human and animal population due to starvation! I would like to make Carbon Curbers and my other progressive friends think if that may have been perhaps the original hidden intention?

Stan (Heretic)

---------------------

Refs:

1. Humanity be proud!

 "Human emissions of carbon dioxide have saved life on Earth from inevitable starvation and extinction due to lack of CO2"

October 2015 Annual GWPF Lecture, Institution of Mechanical Engineers, London.

2. Honestly...

Global Warming data fiddle:

http://www.telegraph.co.uk/comment/11561629/Top-scientists-start-to-examine-fiddled-global-warming-figures.html

3. After the dust settles

http://www.collective-evolution.com/2013/02/08/420000-years-of-data-suggestss-global-warming-is-not-man-made/

There is a consistent ice-core evidence suggesting that each time before an ice age ended, there was a large spike of atmospheric dust. This may suggest that the dust spike may have been in fact the main trigger of glacial meltdown. Where does the dust came from?  Not sure - volcanic perhaps or was the dust blown off the arid deserts of the continental interiors?  I would probably be more inclined towards the latter since the ice age climate is known to have been much drier thus turning the vast areas of land into deserts.  This would also present an automatic feedback mechanism were upon at some point the cooling off of the Earth, the cold climate creates so much continental deserts that the amount of dust blown over the glaciers causes their melt-down.  In this picture a paradoxical carbon-dioxide time lag with respect to the temperature data can be explained by the CO2 (and methane!) out-gassing from the warming oceans, this being the result of the climate warming rather than the cause.

Picture from the above-linked article with my comments:

Update (6-Feb-2017):
http://www.dailymail.co.uk/sciencetech/article-4192182/World-leaders-duped-manipulated-global-warming-data.html

Potatoes and cereals are heart disease risk while dairy, fat and meat are good for you

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- says the new study: "FOOD CONSUMPTION AND THE ACTUAL STATISTICS OF CARDIOVASCULAR DISEASES: AN EPIDEMIOLOGICAL COMPARISON OF 42 EUROPEAN COUNTRIES" .

Results: ...The most significant dietary correlate of low CVD risk was high total fat and animal protein consumption. Additional statistical analyses further highlighted citrus fruits, high-fat dairy (cheese) and tree nuts. ... The major correlate of high CVD risk was the proportion of energy from carbohydrates and alcohol, or from potato and cereal carbohydrates.

Conclusion: Our results do not support the association between CVDs and saturated fat, which is still contained in official dietary guidelines. Instead, they agree with data accumulated from recent studies that link CVD risk with the high glycaemic index/load of carbohydrate-based diets. In the absence of any scientific evidence connecting saturated fat with CVDs, these findings show that current dietary recommendations regarding CVDs should be seriously reconsidered.

(CVD stands for "Cardio Vascular Disease")

by Cecilia Bleszynski (C) 2017

The first graph published in the paper:

is the most interesting in conjunction with the rest of the results, showing that the high consumption of animal fat and protein correlates very well with high blood cholesterol level and at the same time (see for example Fig.4 and 7) the high cholesterol and high consumption of animal fat and protein correlate consistently and strongly with the low cardiovascular and other diseases' risk! That is yet another nail to the coffin of the cholesterol-heart hypothesis and an indication that the blood cholesterol correlation with cardiovascular disease (+ or -) is secondary and spurious while the primary risk factor appears to be related to the carbohydrate contents of the diet! Note that some of the graphs refer to women some for men but the actual correlation factors are similar for men and momen (see Table 1) with the exception of correlations involving BMI and smoking which are opposite for women and men (that is another interesting subject).

Most of the results point consistently and strongly, see for example Fig.10 towards the carbohydrates contents of the diet as being the strongest positive correlator with the cardiovascular disease risk, where as the animal and most plant fats correlate most negatively (that is being protective) against cardiovascular disease, see Table 1, with the notable exception of sunflower oil which correlates strongly and positively with the CVD.

It is also interestingly to notice a strong linear correlation graph with very low data scatter, between the prevalence of raised blood glucose and consumption of carbohydrates plus alcohol ('CA' variable), on Fig.9:

Although diabetes risk was not directly measured in the study, Fig.9 appears to indicate that diabetes risk may be steeply correlated to the total consumption of carbohydrates plus alcohol, and strongly inversely correlated with the consumption of animal fat and protein (see Table 1). For example an increase of the dietary carbohydrate+alcohol contents from 42% to 68% seems to increase the prevalence of high blood glucose (and thus probably diabetes risk as well) by a factor of 3!

The overall results of this study are also remarkably consistent with the original China Study data as published on the Oxford University web site and  discussed on this blog (see my previous posts).

The study is also discussed in the following journalistic article:

"Potatoes and cereals are health risk, while dairy is good for you, says new study".

Lack of benefits from blood glucose-lowering diabetes treatment, doctors confused

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This is the key conclusion from the recently published study.

Glycemic Control for Patients With Type 2 Diabetes Mellitus
Our Evolving Faith in the Face of Evidence

Abstract

...We searched in top general medicine and specialty journals for articles referring to glycemic control appearing between 2006 and 2015 and identified the latest practice guidelines.
...
We identified 16 guidelines and 328 statements. The body of evidence produced estimates warranting moderate confidence. This evidence reported no significant impact of tight glycemic control on the risk of dialysis/transplantation/renal death, blindness, or neuropathy. In the past decade, however, most published statements (77%–100%) and guidelines (95%) unequivocally endorsed benefit. There is also no significant effect on all-cause mortality, cardiovascular mortality, or stroke; however, there is a consistent 15% relative-risk reduction of nonfatal myocardial infarction. Between 2006 and 2008, most statements (47%–83%) endorsed the benefit; after 2008 (ACCORD), only a minority (21%–36%) did.

Conclusions — Discordance exists between the research evidence and academic and clinical policy statements about the value of tight glycemic control to reduce micro- and macrovascular complications.

And journalistic commentary, from the CBC:

New study questions Type 2 diabetes treatment
No evidence glucose-lowering drugs help ward off long-term complications, researchers say

It's a curious case of missing evidence. When a diabetes specialist searched the medical literature looking for proof to support the use of glucose-lowering drugs for Type 2 diabetes, he couldn't find it.

...
His conclusions challenge the conventional wisdom of many medical specialists, and contradict most clinical practice guidelines.

...
"Over 90 per cent of experts were saying that controlling blood sugars tightly was associated with a reduction in your risk of going blind or of needing dialysis or having to undergo an amputation," Montori said. "But when we looked at the evidence for that, we could not see any signal that would suggest that is true despite the question being asked at least since the 1970s."
...
The finding reveals a divergence in professional opinion based on the same set of facts, and it exposes a dilemma in the science of Type 2 diabetes — that doctors don't completely understand the relationship between blood sugar and the disease.

My comments:

1) The lack of benefits from glucose lowering therapies may be explained by the primary cause of the damage being the total carbohydrate overload (Glycemic Load) rather than the blood glucose level.

2) The results are consistent with the research published by R.W.Stout (Lancet, 1969) demonstrating arteriosclerotic plaque production stimulated by glucose and insulin. Reduction of carbohydrate consumption therefore reduces both glycemic load and insulin secretion, reducing the overall risk, especially cardiovascular. Some glucose level controlling drugs only push glucose from one location (blood) into another (tissues) without generally affecting insulin secretion and therefore unchanging the risk, while some other drugs that do increase insulin would also increase the risk.

3) Confusion among medical professionals stems from their attachment to the Western food and lifestyle, unable to consider a possibility that the high carbohydrate nutrition may by itself be the main trigger (if not the cause) of diabetes. In my personal opinion, best remedy would be to allow more free play and competition in the medical field, enabling doctors trained in other countries that may not be subject to the above described mind blocks, to practice legally world-wide, as it is already being widely accepted in other professions such as engineering, scientific research and art.

Stan (Heretic)

Fat and cholesterol-heart disease theory - worldwide hoax perpetrated by American Sugar Association!

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This is now official, documents found and published! If one thinks about the implications, scale and the length of time, it would probably not be surprizing if this were followed by some some serious Crime Against Humanity type investigation against the officials that were involved, and named!

NY Times: How the Sugar Industry Shifted Blame to Fat

The sugar industry paid scientists in the 1960s to play down the link between sugar and heart disease and promote saturated fat as the culprit instead, newly released historical documents show.

The internal sugar industry documents, recently discovered by a researcher at the University of California, San Francisco, and published Monday in JAMA Internal Medicine, suggest that five decades of research into the role of nutrition and heart disease, including many of today’s dietary recommendations, may have been largely shaped by the sugar industry.

“They were able to derail the discussion about sugar for decades,” said Stanton Glantz, a professor of medicine at U.C.S.F. and an author of the JAMA Internal Medicine paper.

The documents show that a trade group called the Sugar Research Foundation, known today as the Sugar Association, paid three Harvard scientists the equivalent of about $50,000 in today’s dollars to publish a 1967 review of research on sugar, fat and heart disease. The studies used in the review were handpicked by the sugar group, and the article, which was published in the prestigious New England Journal of Medicine, minimized the link between sugar and heart health and cast aspersions on the role of saturated fat.

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In 1965, Mr. Hickson enlisted the Harvard researchers to write a review that would debunk the anti-sugar studies. He paid them a total of $6,500, the equivalent of $49,000 today. Mr. Hickson selected the papers for them to review and made it clear he wanted the result to favor sugar. Harvard’s Dr. Hegsted reassured the sugar executives. “We are well aware of your particular interest,” he wrote, “and will cover this as well as we can.”

JAMA paper: Sugar Industry and Coronary Heart Disease Research
A Historical Analysis of Internal Industry Documents

Abstract

Early warning signals of the coronary heart disease (CHD) risk of sugar (sucrose) emerged in the 1950s. We examined Sugar Research Foundation (SRF) internal documents, historical reports, and statements relevant to early debates about the dietary causes of CHD and assembled findings chronologically into a narrative case study. The SRF sponsored its first CHD research project in 1965, a literature review published in theNew England Journal of Medicine, which singled out fat and cholesterol as the dietary causes of CHD and downplayed evidence that sucrose consumption was also a risk factor. The SRF set the review’s objective, contributed articles for inclusion, and received drafts. The SRF’s funding and role was not disclosed. Together with other recent analyses of sugar industry documents, our findings suggest the industry sponsored a research program in the 1960s and 1970s that successfully cast doubt about the hazards of sucrose while promoting fat as the dietary culprit in CHD. Policymaking committees should consider giving less weight to food industry–funded studies and include mechanistic and animal studies as well as studies appraising the effect of added sugars on multiple CHD biomarkers and disease development.

...
RESULTS

SRF’s Interest in Promoting a Low-Fat Diet to Prevent CHD

Sugar Research Foundation president Henry Hass’s 1954 speech, “What’s New in Sugar Research,”12 to the American Society of Sugar Beet Technologists identified a strategic opportunity for the sugar industry: increase sugar’s market share by getting Americans to eat a lower-fat diet: “Leading nutritionists are pointing out the chemical connection between [American’s] high-fat diet and the formation of cholesterol which partly plugs our arteries and capillaries, restricts the flow of blood, and causes high blood pressure and heart trouble… if you put [the middle-aged man] on a low-fat diet, it takes just five days for the blood cholesterol to get down to where it should be… If the carbohydrate industries were to recapture this 20 percent of the calories in the US diet (the difference between the 40 percent which fat has and the 20 percent which it ought to have) and if sugar maintained its present share of the carbohydrate market, this change would mean an increase in the per capita consumption of sugar more than a third with a tremendous improvement in general health.”12

The industry would subsequently spend $600 000 ($5.3 million in 2016 dollars) to teach “people who had never had a course in biochemistry… that sugar is what keeps every human being alive and with energy to face our daily problems.”12

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The SRF’s vice president and director of research, John Hickson, started closely monitoring the field.15
In December 1964, Hickson reported to an SRF subcommittee15 that new CHD research was a cause for concern: “From a number of laboratories of greater or lesser repute, there are flowing reports that sugar is a less desirable dietary source of calories than other carbohydrates, eg,—Yudkin.”15 Since 1957, British physiologist John Yudkin16 had challenged population studies singling out saturated fat as the primary dietary cause of CHD and suggested that other factors, including sucrose, were at least equally important.17,18

Hickson proposed that the SRF “could embark on a major program” to counter Yudkin and other “negative attitudes toward sugar.”15 He recommended an opinion poll “to learn what public concepts we should reinforce and what ones we need to combat through our research and information and legislative programs” and a symposium to “bring detractors before a board of their peers where their fallacies could be unveiled.”15 Finally, he recommended that SRF fund CHD research: “There seems to be a question as to whether the [atherogenic] effects are due to the carbohydrate or to other nutrient imbalance. We should carefully review the reports, probably with a committee of nutrition specialists; see what weak points there are in the experimentation, and replicate the studies with appropriate corrections. Then we can publish the data and refute our detractors.”15

In 1965, the SRF asked Fredrick Stare, chair of the Harvard University School of Public Health Nutrition Department19 to join its SAB as an ad hoc member.20 Stare was an expert in dietary causes of CHD and had been consulted by the NAS,1 National Heart Institute,21 and AHA,22 as well as by food companies and trade groups.19 Stare’s industry-favorable positions and financial ties would not be widely questioned until the 1970s.23

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SRF Funds Project 226: A Literature Review on Sugars, Fats, and CHD
On July 13, 1965, 2 days after the Tribune article, the SRF’s executive committee approved Project 226,31 a literature review on “Carbohydrates and Cholesterol Metabolism” by Hegsted and Robert McGandy, overseen by Stare.10 The SRF initially offered $500 ($3800 in 2016 dollars) to Hegsted and $1000 ($7500 in 2016 dollars) to McGandy, “half to be paid when you start work on the project, and the remainder when you inform me that the article has been accepted for publication.”31 Eventually, the SRF would pay them $650032 ($48 900 in 2016 dollars) for “a review article of the several papers which find some special metabolic peril in sucrose and, in particular, fructose.”31

Diets higher in protein are associated with lower adiposity and do not impair kidney function

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Another myth bites the dust. It appears protein-kidney scare was a BS all along...

The recently published paper:

Diets higher in animal and plant protein are associated with lower adiposity and do not impair kidney function in US adults

Conclusions: Diets higher in plant and animal protein, independent of other dietary factors, are associated with cardiometabolic benefits, particularly improved central adiposity, with no apparent impairment of kidney function.