Since late 2016 we have entered the age of disclosures! Fasten your mental safety belt and enjoy the ride! Heretic

Thursday, December 14, 2017

Vigorous exercizing increases macular degeneration risk

... by 54% in the high group and 28% in the moderate group!

A Nationwide Cohort Study on the Association Between Past Physical Activity and Neovascular Age-Related Macular Degeneration in an East Asian Population, by Tyler Hyungtaek Rim, Hong Kyu Kim, Ji Won Kim, et al, JAMA Ophthalmol. Published online December 14, 2017.


In a propensity score–matched cohort of 211 960 participants, self-reported past vigorous physical activity in men aged 45 to 64 years of age was associated with an increased risk for neovascular age-related macular degeneration, compared with the no physical activity group.


JC said...

I don't believe it.......the correlations are so minor the study probably can't be replicated.

Stan Bleszynski said...

Hi JC,

I agree, the effect is not huge but the significance threshold has been established due to very large sample size. The fact that the effect is not large though consistent, may be indicative of the secondary role of the exercizing. The primary factor is probally (IMHO) the pro-inflammatory effect of metabolic byproducts of exercizing such as lactic acid. It could be interesting to compare the metabolic output of ketgoenic versus carbohydrate based nutrition in exercising.
Happy New Year,
Stan (Heretic)

Anonymous said...

Could it be due to greater sunlight and thus UV ray exposure? Presumably, people who are more into vigorous exercise spend more time outdoors, which exposes their eyes to greater UV radiation.