According to this study (Framingham data):
Increased Small Low-Density Lipoprotein Particle Number
Compared with participants without the MetSyn [Metabolic Syndrome], those with the MetSyn had a higher CVD [Cardio Vascular Disease] event rate. However, among participants with the MetSyn, CVD rates were similar for groups with an elevated versus a lower number of small LDL particles (defined by the sex-specific median).
Conclusions— Small LDL particle number is elevated in the MetSyn, increases with the number of MetSyn components, and most prominently is correlated with triglycerides and HDL-C. Whereas increased small LDL particle number identified the MetSyn with high sensitivity, a higher small LDL particle number was not associated with greater CVD event rates in people with the MetSyn.
Putting it in simple terms: the common misconception that LDL correlates with cardio-vascular disease was caused by bad math! LDL correlated with MetSyn and MetSyn correlates with CVD. Medical establishment leaders with insufficient mathematical training incorrectly believed that correlation supposedly follows the "The law of syllogism" (i.e. if LDL → MetSyn and MetSyn → CVD then LDL → CVD) - BUT IT DOES NOT!
That study simply proved it by finding that in the sub-population of people who already had MetSyn, the number of small LDL particles did not matter! Cholesterol theory is very dead and thoroughly debunked, case closed! Fire them all and move on, next myth please...