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I am reading a lot of papers indicating a connection between skin irritation by heat or by UV, production of Heat-Shock Protein HSP70, D-dimers, autoimmune cascade and cardiovascular infarction due to clotting. See for example this:
1) "S100ß, Matrix Metalloproteinase-9, D-dimer, and Heat Shock Protein 70 Are Serologic Biomarkers of Acute Cerebral Infarction in a Mouse Model of Transient MCA Occlusion" - Jong-Il Choi 1, Sung-Kon Ha 2, Dong-Jun Lim 2, Sang-Dae Kim 2, Se-Hoon Kim 2
J Korean Neurosurg Soc, 2018 Sep;61(5):548-558.
https://pubmed.ncbi.nlm.nih.gov/29724092/
2) "Heatstroke-induced coagulopathy: Biomarkers, mechanistic insights, and patient management",
Toshiaki Iba, Jean Marie Connors, Marcel Levi, Jerrold H. Levy
The Lancet, Open AccessPublished:January 22, 2022
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00006-2/fulltext
Quote from the Lancet paper:
"Platelet count, D-dimer, soluble thrombomodulin, and inflammation biomarkers such as interleukin-6 and histone H3 are promising markers for HSIC [Heat-Stroke Induced Coagulopathy]".
IL6 and D-dimers are also the predictor markers for the cardiovascular events in double or more - vaccinated patients reported by dr. Shankar Chetty in the link I sent 3 days ago.
3) Interview of dr. Shankara Chetty (South Africa) by dr. Peter McCullough on McCullough Report made in the beginning of July 2022.
https://content.blubrry.com/mcculloughreport/Evidence-Based_Medicine_Supports_the_Practice_of_the_Art_of_Medicine.mp3
https://www.americaoutloud.com/?powerpress_pinw=100209-podcast
He is describing lots of clinical detail from his practice. He mentions two early warning factors in his patients forecasting the possibility of cardiac events: IL6 and D-dimer test.
What is interesting, is that he is saying that the cardiac arrest event follows a few days after the covid symptoms which are generally very mild! It goes counterintuitively since it is not the severe flu-like symptoms which may forebode the poor outcome or cardiovascular death during what he calls the "Second Stage" of the omicron infection, but the mild symptoms or even no symptoms! CDr. Chetty is saying that he did NOT notice any significant correlation between the poor Second Stage cardiac outcome and any of the usual comorbidities such as obesity, prediabetes, hypertension etc. He was basically observing healthy patients experiencing unexpected cardiac events! What foreshadows the cardiac event outcome is a very high Interleukin-6 and D-dimer test and also correlation with the covid-vaccinated status, especially double+boosted! He mentions the remarkably effective treatment in those cases with: Promethazine + Aspirine.
