Polish study: half of diabetics on HF LC diet declared themselves cured

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"The effects of so called 'optimal diet' on health status, physical activity
and selected civilization diseases", by Przemysław Fabijański et al., Hygeia Public Health 2011, 46(1): 51-56, www.h-ph.pl, 28.01.2011

"HF LC diet" = High Fat Low Carbohydrate diet (dr. Jan Kwasniewski's "Optimal Diet")

Quotes:

Introduction. So called “optimal diet” – a low-carbohydrate, high-fat
diet, different from Atkins diet – has become very popular in Poland
during the last 20 years. It is very controversial; official dietetics in
Poland claim it is extremely noxious.

Aim [Objectives]. To check what are the effects of so-called “optimal diet” on
health status, frame of mind of people, their physical activity and
diseases including type 2 diabetes.

Material and methods. 436 persons aged 20-75 years, both
women (247) and men (189) were examined. 231 of them applied
“optimal diet” and 205 did not. 86 confirmed they suffered from
type 2 diabetes. All examined persons were inquired with our own
questionnaire.

Results. Quite a lot of statistically significant dependencies were
found to exist. They show us that persons applying the “optimal
diet” might be physically active longer than the persons not applying
it. The majority of the “optimal diet” users claim they got rid of
overweight owing to this diet. Quite many of them claim they
cured themselves of the diabetes or at least the diabetes distress
has distinctly diminished.

Conclusions. The persons applying the “optimal diet” claim they
got rid of overweight or even cured themselves of the diabetes
owing to the diet. Our data do seem to confirm the last reports
(Al-Khalifa et al. 2009).

Fig.1 and Fig.2




Explanations to Fig.1:

"stosujący DO" = Using Optimal Diet,
"nie stosujący OD" = Not using Optimal Diet.

Horizontal axis:

Answers to the question: “Are you suffering from diabetes at present?”

 "Tak" = Yes,
 "Nie, ale kiedyś chorowałem/łam" =  No but I used to suffer from it.


Explanations to Fig.2:

"stan cukrzycy nie zmienił się" = diabetes status hasn't changed

"cukrzyca zaczęła spadać" = diabetes started to recede

"praktycznie cukrzyca zniknęła" = diabetes practically disappeared


Translation of the text between Fig.1 and Fig.2:

"Over half of the respondents were able (in their opinion)
to heal themselves of diabetes using the so-called optimal diet [OD], but it was not possible for anyone (according to respondents' opinions) who did not follow the OD."

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Pathogenic priming

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"Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity".  Journal of Translational Autoimmunity,

Quote:

SARS-CoV-2 has some unexplained pathogenic features that might be related to the table of putative pathogenic priming peptides. Exposure to these specific peptides - via either infection or vaccination - might prime patients for increased risk of enhanced pathogenicity during future exposure due either to future pandemic or outbreaks or via universal vaccination programs. While the mechanisms pathogenesis of COVID-19 are still poorly understood, the morbidity and mortality of SARS has been extensively studied. Thus, the involvement of pathogenic priming in re-infection by COVID-19 is a theoretical possibility; of course no vaccine against SARS-CoV-2 has yet been tested in animals and therefore we do not yet know if pathogenic priming is in fact expected. Such studies should be undertaken before use of any vaccine against SARS-CoV-2 is used in humans.

(from Amy Hayek on facebook,7-May-2020)

"In English this says, the Covid 19 virus has only one sequence that does not have links to human proteins. Thus any part of the virus used in a vaccine could potentially make the vaccine fatal to the humans injected with it."

The following comment is copied from Steve Bashir post on Facebook, 9-Aug-2020 (verify and comment, below, if any inaccuracy is found):

Quote:

The immunity you get from the actual disease is much more enduring, robust, durable and broader spectrum than the immunity you get from vaccines. So there is more protection with immunity derived from the actual disease. There are two types of antibodies produced in an immune response: neutralizing antibodies and binding antibodies. The danger with Coronavirus vaccines is a phenomenon called 'pathogenic priming'.

Neutralizing antibodies are good. Binding antibodies however, are produced when you try to vaccinate against a Coronavirus. These binding antibodies act like Velcro on your cells' receptors. So the virus sticks to the cells and makes you much more sick.

If you get exposed to Coronavirus through the vaccine, it actually 'primes' your system. So you get much sicker the next time the virus comes around. For example, in the 1960's a MERS (Coronavirus) vaccine was tested on children. But when they were actually challenged by disease itself, they all became horrendously sick and two of them died.

In 2014 Sanofi worked with the NIH to develop a Dengue vaccine. And they saw some of those same pathogenic priming signals during the clinical trials. But ignored them. They gave that vaccine to hundreds of thousands of kids in the Philippines and they all got an immune response. But when the Dengue came back around, the kids who were vaccinated were devastated and 600 of them died. There are criminal charges right now in the Philippines trying public health officials, who were involved in that decision.

Additionally, vaccine manufacturers are free from liability. So they can't be sued, even if things go dreadfully wrong. And there is no adequate safety testing done. Because it's costly and manufacturers don't do it, bcz they are not required to. This 'pathogenic priming' effect is the single most important and dangerous issue when it comes to a Coronavirus vaccine. As no one knows how devastating it can turn out to be.

More reference links:

"Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity", by JamesLyons-Weiler,9 March 2020

"A new study reveals insights into why doctors and researchers are cautioning against the reckless race for a COVID-19 vaccine.", May 18, 2020

"Dengue vaccine fiasco leads to criminal charges for researcher in the Philippines", By Fatima Arkin, Apr. 24, 2019

Research/Patent on Chloroquine treatment against DNA damage

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"...exposure to chloroquine prior to irradiation increased cell Survival by 30%." 

  US 2005/0014785 A1 

 Authors: 

Michael B. Kastan, Cordova, TN (US); 

Christopher Bakkenist, Cordova, TN (US);

Mark McCamish, Cupertino, CA (US) 

 Pub. Date: Jan. 20, 2005 

 Note: a Patent is not a proof that the invention works! 

 Quotes:

ABSTRACT The present invention provides methods and compositions for the treatment of DNA damage related disorders. One embodiment is a method for the inhibition of Side effects asSociated with chemotherapeutic and radiotherapeutic agents using chloroquine compounds. Another embodiment is a method for treatment and/or prevention of lethal or Sub-lethal radiation toxicities associated with terrorist acts or war.

BRIEF DESCRIPTION OF THE FIGURES 0007 FIG. 1 shows a Kaplan-Meier survival curve of C57/BL6 mice after exposure to 8 Gy total body irradiation (TBI). Half of the cohort received a dose of chloroquine (dashed line) by either i.p. injection (1.75 mg/kg or 3.5 mg/kg) or in their drinking water (3.5 mg/kg or 7 mg/kg) the day before the TBI. The one mouse which died in the chloroquine-treated group received 1.75 mg/kg by i.p. injection.

0008 FIG. 2 shows that chloroquine treatment enhances survival after TBI by enhancing recovery of hematopoietic progenitor cells. Five mice received 3.5 mg/kg chloroquine (C) by i.p. injection 24 and 4 hours prior to TBI (bars with diagonal Stripes). Five mice received no chloroquine (stippled bars). Fourteen days after irradiation, the cellular ity (open bars) of hematopoietic tissues (spleen, thymus, bone marrow) was assessed by a blinded observer on a scale of 0-3 with 3 being normal cellularity. The bars represent the average cellularity of the tissues from the 5 mice in each group.

0009 FIG.3 shows a Kaplan-Meier survival curve of AT mice after exposure to 8 GyTBI. Half of the cohort received a dose of 3.5 mg/kg chloroquine (CHL; dashed line) by i.p. injection 24 and 4 hours prior to the TBI.

0010 FIG. 4 demonstrates that chloroquine treatment prevents the development of tumors in Eul-myc mice. After weaning, a cohort of transgenic mice expressing the c-myc oncogene were started on chloroquine (CHL) at 7.0 mg/kg in the drinking water ((+), solid line). Within 100 days, all of the mice with no drug in the water had died of leukemia, while none of the cohort of mice on drug had Succumbed. The latter group of mice was then divided into two groups (timing of this event depicted by heavy arrow), one group of which was taken off of chloroquine ((-), dashed line) and the other group of which was started on i.p. injections of 3.5 mg/kg of chloroquine once a week. Within a month, all of the mice taken off of chloroquine had developed malignan cies and all of the mice on the weekly i.p. injections remained tumor-free for months.

0011 FIG. 5 illustrates that chloroquine treatment reduces the development of tumors in mice injected with the potent chemical carcinogen, 3-methylcholanthrene (3-MC). Chloroquine (CHL, 3.5 mg/kg) was given by i.p. injection 24 and 4 hours prior to 3-MC injection in 30 mice and 30 mice received the carcinogen with no chloroquine pretreat ment. The percentage of animals remaining tumor-free is plotted. Statistical significance, log rank test P-0.0001.

0012 FIG. 6 demonstrates that chloroquine treatment reduces the development of tumors in mice exposed to ionizing radiation in a protocol that induces thymic lym phomas. Chloroquine (CHL, 3.5 mg/kg) was given by i.p. injection 24 and 4 hours prior to irradiation in four Successive weeks and animals were subsequently observed for the development of tumors. Statistical Significance, log rank test P=0.0012.

0013 FIG. 7 shows tumor incidence in wildtype mice receiving either placebo or CHQ before 3-MC injection. CHQ markedly protects from tumor development.

0014 FIG. 8 shows tumor incidence in ATM-null mice receiving either placebo or CHQ before 3 MC injection. CHQ does not protect from tumor development.

0015 FIG. 9 shows tumor incidence in p53-null mice receiving either placebo or CHQ before 3 MC injection. CHQ does not protect from tumor development.

0016 FIG. 10 demonstrates the efficacy of two chloroquine compounds in preventing, in Varying degree, the change in coat color in mice treated with 8 GY radiation.

------------ Update 14-Aug-2020 -----------------

"Hydroxychloroquine-loaded hollow mesoporous silica nanoparticles for enhanced autophagy inhibition and radiation therapy",by Yan Li et al., 25-June-2020