Recovered raw data of old study undermines 40y of dietary dogma

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SciAm article: Records Found in Dusty Basement Undermine Decades of Dietary Advice
Raw data from a 40-year-old study raises new questions about fats
By Sharon Begley, STAT on April 19, 2017

Quote:

Ramsden, of the National Institutes of Health, unearthed raw data from a 40-year-old study, which challenges the dogma that eating vegetable fats instead of animal fats is good for the heart. The study, the largest gold-standard experiment testing that idea, found the opposite, Ramsden and his colleagues reported on Tuesday in BMJ (formerly the British Medical Journal).

Although the study is more than just another entry in the long-running nutrition wars—it is more rigorous than the vast majority of research on the topic—Ramsden makes no claims that it settles the question. Instead, he said, his discovery and analysis of long-lost data underline how the failure to publish the results of clinical trials can undermine truth.
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The coleader of the project was Dr. Ancel Keys, author of the Seven Countries Study, Time cover subject, and the most prominent advocate of replacing saturated fat with vegetable fat. “The idea that there might be something adverse about lowering cholesterol [via vegetable oils] was really antithetical to the dogma of the day,” Bob Frantz said.

His father, he said, “was always committed to discovering the truth. He would be pleased this is finally coming out.”

From The Telegraph "Modern dunce's cap"

I beg to differ. I doubt if Dr. Ivan Frantz would be proud of publishing the truth, because he could have but he didn't! I think he was afraid of the truth! Like many academics, intellectuals and most people I knew worked with.   Not only Dr. I. Frantz kept the study's most important data unpublished but also actively obfuscated it by publishing a misleading partial summaries and whitewashed watered-down inconclusive "conclusions".

Half-truth = full lie!

Because of Dr. Ivan Frantz' and other fake scientists' failure to publish the truth, What followed was 40-more years of suffering by millions of people from preventable diseases, due to bad dietary advise and corporate self-served food marketing that was based on the academically-supported half-truth, lies and distortions!

United Stated needs no external enemy - it is being destroyed by their own luminaries and the establishment through half-truth, lies and deception.

Bob Frantz, Dr. Franz's son, who rediscovered the hidden records and got them published, can't really feel proud of his father, but he definitely deserves to be proud of himself and be praised for bringing the truth! He is also lucky to have survived his father's bad diet at home, as a child.

Reference:
Appendix: Supplementary material [posted as supplied by author
Part 1: MCE supporting materials and historical context
Tribute to Dr. Ivan Frantz in leading the Minnesota Coronary Experiment team
Reared on Margarine and to the Tune of Spinning Ultracentrifuges:
A Son’s Recollections of Ivan D. Frantz, Jr. During the Early Days of Lipid Research
Robert P. Frantz, M.D.

Low fat diet rises risk of early death by a quarter

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New study reported here:

•  Laura Donnelly, health editor, in barcelona 

29 AUGUST 2017 • 11:39AM

Low-fat diets could raise the risk of early death by almost one quarter, a major study has found.

The Lancet study of 135,000 adults found those who cut back on fats had far shorter lives than those enjoying plenty of butter, cheese and meats.

Researchers said the study was at odds with repeated health advice to cut down on fats.

Reference:

Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study

Quote:

Findings
During follow-up, we documented 5796 deaths and 4784 major cardiovascular disease events. Higher carbohydrate intake was associated with an increased risk of total mortality (highest [quintile 5] vs lowest quintile [quintile 1] category, HR 1.28 [95% CI 1.12–1.46], ptrend=0.0001) but not with the risk of cardiovascular disease or cardiovascular disease mortality. Intake of total fat and each type of fat was associated with lower risk of total mortality (quintile 5 vs quintile 1, total fat: HR 0.77 [95% CI 0.67–0.87], ptrend<0.0001; saturated fat, HR 0.86 [0.76–0.99], ptrend=0.0088; monounsaturated fat: HR 0.81 [0.71–0.92], ptrend<0.0001; and polyunsaturated fat: HR 0.80 [0.71–0.89], ptrend<0.0001). Higher saturated fat intake was associated with lower risk of stroke (quintile 5 vs quintile 1, HR 0.79 [95% CI 0.64–0.98], ptrend=0.0498). Total fat and saturated and unsaturated fats were not significantly associated with risk of myocardial infarction or cardiovascular disease mortality.

----- Update 8/09/2017 -----
Another article, from the NYT, commenting on that study:

New Study Favors Fat Over Carbs

Quote:

Compared with people who ate the lowest 20 percent of carbohydrates, those who ate the highest 20 percent had a 28 percent increased risk of death. But high carbohydrate intake was not associated with cardiovascular death.
People with the highest 20 percent in total fat intake - an average of 35.3 percent of calories from fat - had about a 23 percent reduced risk of death compared with the lowest 20 percent (an average of 10.6 percent of calories from fat). Consuming higher saturated fat, polyunsaturated fat and monounsaturated fat were all associated with lower mortality. Higher fat diets were also associated with a lower risk of stroke.

They finally proved correlation between saturated fat and heart disease...

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... and it is inverse!

From Wiki

In case you missed it, see the study link and the post on Diet Doctor.  See also an interesting post on the High Fat Hep-C Diet blog.  In a nutshell:

Each additional 5% of saturated fat (SFA) contents was associated with 17% lower risk of ischemic heart disease (IHD)  : Hazard Ratio 0.83 +/- 0.1.

RESULTS:
During 12 y of follow-up, 1807 IHD events occurred. Total SFA intake was associated with a lower IHD risk (HR per 5% of energy: 0.83; 95% CI: 0.74, 0.93). Substituting SFAs with animal protein, cis monounsaturated fatty acids, polyunsaturated fatty acids (PUFAs), or carbohydrates was significantly associated with higher IHD risks (HR per 5% of energy: 1.27-1.37). Slightly lower IHD risks were observed for higher intakes of the sum of butyric (4:0) through capric (10:0) acid (HRSD: 0.93; 95% CI: 0.89, 0.99), myristic acid (14:0) (HRSD: 0.90; 95% CI: 0.83, 0.97), the sum of pentadecylic (15:0) and margaric (17:0) acid (HRSD: 0.91: 95% CI: 0.83, 0.99), and for SFAs from dairy sources, including butter (HRSD: 0.94; 95% CI: 0.90, 0.99), cheese (HRSD: 0.91; 95% CI: 0.86, 0.97), and milk and milk products (HRSD: 0.92; 95% CI: 0.86, 0.97).

Interestingly, equal-caloric substitution of 5% of SFA in the diet with:

•  any carbohydrate type (low GI, medium GI or high GI),
•  mono-unsaturated fats,
•  polyunsaturated fats,
•  animal protein,

- correlated positively with IHD, while substitution of SFA with vegetable protein correlated negatively! (Correlation calculations were corrected against known confounding factors such as age, sex, BMI, waist circumference, educational level, physical activity level, smoking status, alcohol intake, energy-adjusted intakes of cholesterol, fiber, and vitamin C.

Stan (Heretic)

Coconut fat - proof of no harm and amazing benefits!

No I have not sold out (yet) to coconut marketing, I just think this is important! 8-:)

1. "Cholesterol, coconuts, and diet on Polynesian atolls: a natural experiment: the Pukapuka and Tokelau island studies."

http://www.ncbi.nlm.nih.gov/pubmed/7270479

Prior IA, Davidson F, Salmond CE, Czochanska Z.

Am J Clin Nutr. 1981 Aug;34( 8 ) :1552-61

Quotes:

...Vascular disease is uncommon is both populations and there is no evidence of the high saturated fat intake having a harmful effect in these populations.... ...

... The migration of Tokelau Islanders from their atolls to the very different environment of New Zealand is associated with changes in lipids that indicate increased risk of atherogenesis. This is associated with an actual fall in saturated fat intake to around 41% of energy, an increase in dietary cholesterol intake to 340 mg, and an increase in carbohydrate and sugar. Lipid changes include increased total cholesterol, higher LDLC and triglycerides, and lower HDLC levels (16) ...

2. "Doctor says an oil lessened Alzheimer's effects on her husband". The clock face drawings below are before, after 2weeks and after 37 days.

Dr. Mary Newport and her husband.  Dr. Mary's husband "clock" drawings below, original - left, after coconut treatment - right.  (picture restored from backup) 

http://www.tampabay.com/news/aging/article879333.ece (Note: the original link has died)

Take a look at the following quotes:

"Ketones are a high-energy fuel that nourish the brain," VanItallie said, explaining that when you are starving, the body produces ketones naturally. When digested, the liver converts MCT oil into ketones. In the first few weeks of life, ketones provide about 25 percent of the energy newborn babies need to survive.

Dr. Veech has been working with ketones for more than 40 years and has become a valuable resource to the Newport family. Currently, he is working for the military, looking into ketones as a way to improve the performance of troops in severe conditions.

and from the readers' comments below the article, by Dr. Mary Newport:

by Mary Nov 2, 2008 6:52 PM From Dr. Mary: Any non-hydrogenated coconut oil would have the ketone effect, contains no cholesterol. Steve's total cholesterol has remained [less than] 200, HDL and LDL are better than ever. It's reputation as "oil clogging fat" is a myth from the 1950's.

P.S.

I found those article links on Stephan's blog (highly recommended!). I thought the subject deserves a separate thread. Other good source on the benefits of coconut (and other fats) is Weston A. Price Foundation .


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Follow up after 9 years (better late than never!)
22-March-2017

Article:

http://www.realfarmacy.com/coconut-oil-alzheimers-clinical-study/

by Paul Fassa

Quote:

Dr. Mary Newport, desperate after orthodox medical attempts failed her husband’s dwindling dysfunction from Alzheimer’s, discovered coconut oil and rescued him from having to be put away in a special home.
His remarkable recovery went viral on the internet and Dr. Newport wrote a 2011-12 bestseller, Alzheimer’s Disease: What if There Was a Cure?Both the Internet’s coverage and her book started an international grassroots movement of folks with very early dementia, even just brain fog and senior moments, trying themselves or helping relatives diagnosed with Alzheimer’s. Thus creating a wave of success reports and testimonial videos.

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