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Saturday, June 25, 2011

70g carbs per day diet reverses diabetes in 2 months!

An apparently ketogenic diet consisting of ~70g of carbohydrates/day and 49g protein/day reversed type 2 diabetes in 11 patients.  During the 8 week course of the study, the patients' metabolic energy was derived primarily from fat, that is: 13.4g/day of dietary fat plus an average of 227g of body fat consumed in a day.  (They lost an average of 12.7kg of body fat per person, over 8 weeks!)

Here is the study Diabetologia DOI 10.1007/s00125-011-2204-7

Title: "Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol", E. L. Lim, K. G. Hollingsworth, B. S. Aribisala, M. J. Chen, J. C. Mathers, R. Taylor

(Thanks Dav0 for alerting me to this study!)


Peter said...

Stan, I think we have to note that weight gain post study was almost a kilo a week (average gain 3.1kg in the first month post study) and three patients were clinically diabetic again by this time (a quarter of the participants). Long term there is no hope for any of them unless they keep themselves so hungry as to have a low carbohydrate intake while ever they eat a "balanced diet". Some might do it, the Iron Few... Most cannot live with this sort of hunger. The fact that the rise in insulin was statistically ns should not blind us to the fact this is a product of small numbers and the routine wide SD in plasma insulin levels. The p < 0.05 fall in FFAs says insulin is physiologically elevated and easily explains the weight gain.

And predicts catastrophe.


Anonymous said...


Anonymous said...

Actually, just found this link:

DePaw said...

Diet eaten: 49g protein, 70g carb, 13.4g fat... 596.6 calories, 32.9% from protein, 46.9% from carbs, 20.2% from fat.

Add body fat: 12.7kg over 8 weeks is 226.8g per day. Add this to the diet: 49g protein, 70g carb, 240.2g fat... 2267.9 calories, 8.6% from protein, 12.3% from carbs, 95.3% from fat.

Alternative headline: "95% calories from fat diet reverses diabetes".